- Basic information
- CohesinDB ID: CDBP00418372
- Locus: chr21-36233845-36235845
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Data sourse: GSE206145-GSE177045, GSE104888, ENCSR230ZWH, GSE72082, ENCSR000ECS, GSE25021, GSE108869, ENCSR000EDW, GSE115602, ENCSR917QNE, GSE67783, GSE86191, GSE138405, GSE76893, ENCSR703TNG, ENCSR000EEG, ENCSR338DUC, ENCSR000BLS, ENCSR000BTQ, ENCSR167MTG, GSE129526, GSE111913, ENCSR054FKH, ENCSR000EDE, ENCSR153HNT, GSE68388, GSE126990, GSE50893, ENCSR748MVX
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Cell type: MCF-7, GM12892, Hela-Kyoto, HCT-116, Hep-G2, GM2610, A-549, HeLa-S3, RT-112, K-562, Liver, HSPC, HuCC-T1
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 13% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.856
- Subunit: NIPBL,SA1,Rad21,SMC1,SMC3ac,SA2,Mau2,SMC3
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
92% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"5_TxWk": 59%,
"7_Enh": 18%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: TRIM25, PGR, FOXA1, SUZ12, PRDM1, PAX5, MITF, ZNF736, ELF1, ZNF121, ETV1, ESR1, HDAC8, CTCF, BAF155, EP300, E2F1, TFAP2C, EED, NANOG, CHD8, CDK9-HEXIM1, TOP2A, ZBTB48, ZSCAN5A, ERG, MYC, TOP1, RXRA, BATF3, GABPA, APC, XRCC5, STAT3, NKX3-1, IKZF1, NR3C1, CEBPB, CREB1, EZH2, GRHL2, SPI1, IRF1, GATA2, ETV5, RUNX1, NKX2-2, ZFX, SMAD3, TET2, ZNF384, RUNX2, ARNT, PBX4, DAXX, FOS, TERF1, PIAS1, ZMYM3, ZNF3, GSPT2, ASH2L, TCF3, FOXP1, STAG1, ZNF283, CBX3, FOXA2, WT1, ZBTB33, CDK9, HOXB13, YY1, RELA, HIF1A, SKIL, GATA3, BATF, ZNF143, PLAG1, NCOA3, NR2F2, TCF7L2, ELF3, TBX21, AR, EGLN2, HSF1, RNF2, BRD4, MAZ, AHR
- Target gene symbol (double-evidenced CRMs): MORC3,DOP1B,SMIM11A,CBR3
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 10
- Number of somatic mutations (non-coding): 0
- Related genes and loops