- Basic information
- CohesinDB ID: CDBP00418373
- Locus: chr21-36236082-36238447
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Data sourse: GSE93080, ENCSR000DZP, GSE67783, GSE86191, GSE111913, GSE85526, GSE206145-NatGen2015, ENCSR000BMY, ENCSR153HNT, GSE50893, GSE131577
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Cell type: GM2630, Fibroblast, HCT-116, HL-60, HEKn, GM12878, GM2588, RT-112, K-562, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 3% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.889
- Subunit: SA1,Rad21,SMC1,SA2,SMC3
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
92% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"5_TxWk": 55%,
"4_Tx": 30%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: RUNX1, POU2F2, MEF2B, BCL6, SMC1A, CHD8, EBF1, RBPJ, ZFX, MTA2, WT1, CBX8, DDX5, NBN, TRIM22, HOXB13, ERG, RELA, HDGF, ZNF384, ASCL1, JUNB, MYC, RUNX3, ARNT, BATF, STAT3, MAX, XRCC5, PAX5, ETV6, IKZF1, MED1, TEAD3, ELF1, SNAI2, NR2F1, EZH2, MLLT1, PKNOX1, MED, CTCF, TCF12, SND1, SPI1, BCL11A, TBX21, BHLHE40, SP1, ZNF257, DPF2, GATAD2B, MXD3, IRF4, ATF7, ZBTB26, IKZF2, TCF3, RELB, NCOR2, STAG1, AHR, EED
- Target gene symbol (double-evidenced CRMs): SMIM11A,DOP1B,MORC3,CBR3
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 42
- Number of somatic mutations (non-coding): 0
- Related genes and loops