- Basic information
- CohesinDB ID: CDBP00418374
- Locus: chr21-36238704-36240434
-
Data sourse: GSE67783, GSE86191, GSE116868, ShirahigeLab, ShirahigeLab-NatGen2015, ENCSR153HNT
-
Cell type: RPE, Fibroblast, HCT-116, MB157, K-562, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 2% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.933
- Subunit: SA1,Rad21,SA2,SMC1
-
CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
-
Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
92% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
-
Chromatin annotation:
"5_TxWk": 58%,
"4_Tx": 31%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
-
Co-bound Transcriptional factors: GLIS1, TRP47, POU2F2, CHD8, SMC1A, ZSCAN5D, FOXA2, MYCN, MEIS1, TBL1X, ZFX, ZNF263, XBP1, AGO1, ZBTB48, WT1, HMGN3, TET2, CDK9, MLL4, ERG, YY1, RELA, OGG1, ATF3, MYC, RUNX2, SP140, GRHL3, POU5F1, HIF1A, CBFB, MECOM, STAT3, NCAPH2, ZNF143, AGO2, MITF, DNMT3B, SRSF3, TRIM28, KDM6B, EZH2, ZNF3, TP53, OCA2, ESR1, CTCF, BCL11A, SPI1, POU2F1, TFAP2A, KLF1, ARRB1, AR, GSPT2, RXR, REST, HEXIM1, TFIIIC, HSF1, FLI1, NOTCH3, BRD4, TCF3, E2F1, MAZ, AATF, SMC3, STAG1, AHR, EED
- Target gene symbol (double-evidenced CRMs): CBR3,DOP1B,MORC3,SMIM11A
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 37
- Number of somatic mutations (non-coding): 0
- Related genes and loops