- Basic information
- CohesinDB ID: CDBP00418380
- Locus: chr21-36250101-36251132
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Data sourse: ENCSR000BLD, GSE67783, GSE86191, ShirahigeLab, ENCSR153HNT
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Cell type: RPE, H1-hESC, HCT-116, K-562, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.944
- Subunit: SA1,Rad21
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: non-Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
89% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"5_TxWk": 43%,
"4_Tx": 38%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: RUNX1, BRD1, MYCN, POU5F1, CDK7, ZFX, XBP1, ZBTB48, ZSCAN5A, WT1, FOXA1, SMAD3, SUZ12, CDK9, ERG, KDM1A, YY1, RELA, NOTCH1, NEUROD1, ATF3, RUNX2, ETS1, SMARCA4, EOMES, CHD7, SP140, SOX11, OTX2, GATA3, GABPA, TAL1, MAX, ZNF143, DNMT3B, MED1, NR3C1, CEBPB, NCOA3, MYB, KMT2A, NEUROG2, CREB1, EZH2, LMO2, OCA2, BMPR1A, ZNF334, T, TCF12, CTCF, ARRB1, ARID5B, LMO1, AR, GATA6, HSF1, ASH2L, HNRNPLL, BRD4, MAZ, AATF, STAG1, RBPJ, EED
- Target gene symbol (double-evidenced CRMs): DOP1B,CHAF1B,MORC3
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 5
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000142197,
ENSG00000159256,
ENSG00000159259,
- Related loop:
chr21:34350000-34375000~~chr21:36225000-36250000,
chr21:36125000-36150000~~chr21:36225000-36250000,
chr21:36225000-36250000~~chr21:36325000-36350000,
chr21:36245123-36246662~~chr21:36330384-36331754,
chr21:36245246-36246544~~chr21:36329821-36332549,
chr21:36250000-36275000~~chr21:36350000-36375000,
chr21:36250000-36275000~~chr21:36375000-36400000,
chr21:36250000-36275000~~chr21:36550000-36575000,
chr21:36253261-36254421~~chr21:36319310-36321320,