- Basic information
- CohesinDB ID: CDBP00418391
- Locus: chr21-36272357-36274134
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Data sourse: GSE67783, GSE86191, GSE206145, GSE206145-NatGen2015, ENCSR153HNT
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Cell type: RPE, Fibroblast, HCT-116, K-562, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.944
- Subunit: SA1,Rad21,SA2
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: non-Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
89% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"5_TxWk": 71%,
"4_Tx": 17%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: PGR, CHD8, MAFG, ZSCAN5D, ZNF316, ZFX, MEIS2, XBP1, ZNF317, WT1, ZBTB48, MAFF, FOXA1, POU4F2, PBX2, ERG, YY1, RELA, CDK6, PRDM1, SP140, GABPA, ZEB1, SCRT2, EZH2, ESR1, C11orf30, HDAC8, CTCF, JUN, MAFK, AR, GATA2, EGLN2, HNRNPLL, BRD4, SCRT1, MAZ, TFAP2C, EED
- Target gene symbol (double-evidenced CRMs): MORC3,DOP1B,CHAF1B
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 4
- Number of somatic mutations (non-coding): 0
- Related genes and loops