- Basic information
- CohesinDB ID: CDBP00418394
- Locus: chr21-36276517-36277955
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Data sourse: GSE67783, GSE86191, GSE98367, GSE111913, ShirahigeLab, ShirahigeLab-NatGen2015, ENCSR153HNT
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Cell type: RPE, Fibroblast, HCT-116, RT-112, K-562, HSPC, Macrophage
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 2% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.922
- Subunit: SA1,Rad21,SA2,SMC1
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
89% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"5_TxWk": 50%,
"4_Tx": 38%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: GLIS1, POU2F2, CHD8, SMC1A, CEBPA, POU5F1, EBF1, TOP2A, KDM4C, ZFX, KLF13, XBP1, MYCN, WT1, ZBTB48, KDM4B, STAT1, ZSCAN5A, ZNF770, ERG3, DDX5, FOXA1, ERG2, RELA, CREBBP, ZNF384, ATF3, EZH1, CDK6, SP140, GRHL3, ARNT, PGR, MECOM, TAL1, ETV6, MAX, ZNF143, IKZF1, GATA1, NR2F6, MED1, PLAG1, CEBPG, CEBPB, ESRRA, NCOA3, ELF1, NR3C1, NR2F1, EZH2, TP53, OCA2, ZIM3, USF2, MYOD1, JUN, CTCF, AR, GATA2, ZBTB7A, ZNF263, RNF2, NOTCH3, BRD4, MAZ, SMC3, STAG1, ZNF316, EED
- Target gene symbol (double-evidenced CRMs): SMIM11A,DOP1B
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 35
- Number of somatic mutations (non-coding): 0
- Related genes and loops