- Basic information
- CohesinDB ID: CDBP00418397
- Locus: chr21-36281766-36283404
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Data sourse: GSE67783, GSE206145, GSE206145-NatGen2015, ENCSR000BMY, ENCSR153HNT, GSE68388, GSE50893
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Cell type: RPE, GM2630, Fibroblast, GM2610, GM12878, K-562, HSPC, HuCC-T1
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 2% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.911
- Subunit: SA1,Rad21,SMC1,SA2,Mau2
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
89% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"5_TxWk": 59%,
"4_Tx": 29%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: RUNX1, GLIS1, POU2F2, MAFG, ZNF316, CEBPA, ZSCAN5C, ZNF778, ZNF534, ZNF600, XBP1, ZSCAN21, ZBTB48, ZSCAN5A, MAFF, FOXA1, ZBTB17, PATZ1, ERG3, SUZ12, CBX8, MEF2C, SP4, HOXB13, PRDM10, ERG, RELA, ATF3, MYC, OSR2, RUNX3, CDK8, IKZF1, ZNF639, SFPQ, MED1, CEBPB, SP7, ZNF629, OCA2, TP73, MLL, C11orf30, SETDB1, CTCF, MAFK, BHLHE40, FOSL2, IKZF2, BRD4, AHR, EED
- Target gene symbol (double-evidenced CRMs): DOP1B,SMIM11A
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 14
- Number of somatic mutations (non-coding): 0
- Related genes and loops