- Basic information
- CohesinDB ID: CDBP00418400
- Locus: chr21-36288047-36291537
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Data sourse: GSE126634, GSE111537, GSE165895, ENCSR000EFJ, GSE93080, ENCSR000EAC, ENCSR000DZP, GSE67783, GSE86191, GSE152721, GSE206145-NatGen2015, GSE120943, GSE116344, GSE98367, GSE206145, GSE62063, ENCSR000BMY, GSE131956, ENCSR000HPG, ENCSR153HNT, GSE50893
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Cell type: RH4, GM2610, GM19240, HSPC, RPE, GM2630, Fibroblast, IMR-90, K-562, GM18486, HFFc6, GM18951, SNYDER, Monocytes, GM18505, GM12878, GM12891, GM2588, GBM39, GM19239, Macrophage, Ramos, GM12892, HCT-116, OCI-AML-3, HAP1
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 11% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.711
- Subunit: NIPBL,SA1,Rad21,SMC1,SA2,Mau2,SMC3
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: TSS,TES,Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
89% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"5_TxWk": 43%,
"7_Enh": 20%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: RELA, HOXB13, SMARCA4, ZFX, GTF2B, BRD4, ZSCAN5A, USF2, MAX, CTCF, USF1, MITF
- Target gene symbol (double-evidenced CRMs): DOP1B,SMIM11A
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 76
- Number of somatic mutations (non-coding): 3
- Related genes and loops