- Basic information
- CohesinDB ID: CDBP00418403
- Locus: chr21-36295324-36296187
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Data sourse: ENCSR000BLD, GSE67783, GSE86191, GSE98367, GSE111913, GSE206145-NatGen2015, ENCSR153HNT
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Cell type: H1-hESC, Fibroblast, HCT-116, RT-112, K-562, HSPC, Macrophage
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 2% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.922
- Subunit: SA1,Rad21,SMC1
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: TSS,TES
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
89% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"5_TxWk": 59%,
"15_Quies": 18%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: FOXO1, PGR, ZSCAN5C, SOX2, MEIS2, XBP1, KDM4B, FOXA1, SUZ12, PBX2, UBTF, MLL4, ZFHX2, TFAP4, HDGF, LYL1, ATF3, NFIC, RUNX3, CBFB, KLF1, MECOM, SMARCE1, PAX5, TP63, MITF, BACH2, CDX2, MAF, INTS11, KLF5, ELF1, ZNF121, BCLAF1, KLF6, TRIM28, RBM39, JMJD1C, LMO2, ESR1, MLL, OCA2, ZNF217, HDAC8, SMAD5, USF2, CTCF, SND1, TCF12, BAF155, E4F1, ARID5B, MNT, LMO1, GATA6, JUN, DPF2, NFE2L2, EP300, E2F6, TRIM24, RFX5, IRF4, CREB3, SOX6, RAD51, TEAD4, KMT2B, ZNF175, GTF2F1, EHMT2, RBPJ, EED, TFAP2C, JARID2, POU2F2, CHD8, NANOG, ZSCAN5D, MYCN, POU5F1, RUNX1T1, ID3, TOP2A, CTBP1, CDK7, MTA2, ZBTB48, ZSCAN5A, STAT1, MLLT3, GATAD1, DDX5, NBN, ERG2, SAP130, TBP, ERG, ASCL1, OGG1, ZNF341, MYC, EZH1, SMARCA4, ARID1B, RAD21, GRHL3, PROX1, RXRA, FOXK2, NKX2-1, GABPA, STAT3, XRCC5, NKX3-1, IKZF1, LEF1, TERF2, CD74, NFRKB, RCOR1, NFE2, NR3C1, ESRRA, SRSF3, ZNF750, STAT5B, CEBPB, KMT2A, CREB1, ZBTB11, EZH2, GRHL2, TRPS1, GABPB1, PHF8, ZHX2, ELF4, SPI1, TFE3, EHF, IRF1, HDAC2, GATA2, INTS13, ETV1, GATAD2B, ZSCAN29, FLI1, HCFC1, MXI1, SMARCA5, RELB, NFIL3, NCOA2, NFYB, ETV5, RUNX1, SMC1A, BCL6, HDAC1, CEBPA, CBX1, LDB1, SIN3A, ZFX, NKX2-2, SMAD3, ZNF770, ERG3, TRIM22, MEF2A, CREBBP, ZBTB2, NOTCH1, IRF2, RUNX2, CDK6, GATA4, GR, ARNT, PBX4, NRF1, ZNF48, ATF2, HMBOX1, SMAD4, NFYA, ETV6, NCAPH2, MAFB, FOS, CDK8, SUPT5H, ZEB2, HMGXB4, MED1, CBFA2T3, ZEB1, TEAD3, TERF1, MYB, SCRT2, ZMYM3, PIAS1, NR1H2, C11orf30, L3MBTL2, EVI1, MAFK, BCL11A, NIPBL, USF1, HNF4A, SP1, VDR, IKZF5, REST, ZBTB7A, RBM25, ATF7, ASH2L, HNRNPLL, CTBP2, MBD2, BCOR, TCF3, FOXP1, AATF, SMC3, STAT2, NCOR2, STAG1, MLLT1, NFATC3, SKI, TRP47, CBFA2T2, MEF2B, FOXA2, AGO1, EBF1, RBBP5, MTA3, MEIS1, CBX3, CREM, GTF2B, WT1, SNAI2, MEF2C, CDK9, HOXB13, BCL3, KDM1A, YY1, RELA, ZNF589, TARDBP, NEUROD1, KAT2B, SP140, ZFP36, HIF1A, SKIL, ZNF639, TCF4, GATA3, OTX2, BATF, MGA, TAL1, MAF1, MAX, SPIB, ZNF143, AGO2, GATA1, MTA1, KLF4, ZNF592, NCOA3, GFI1B, NR2F1, NEUROG2, KDM5B, TP53, ZNF687, PKNOX1, NFKB1, ELF3, ARRB1, TBX21, BHLHE40, AR, ARID4B, TAF1, ZBTB40, RXR, EGLN2, HEXIM1, TFIIIC, HSF1, ZBTB26, NOTCH3, BRD4, ILF3, IKZF2, JUND, RNF2, MAZ, NCOR1
- Target gene symbol (double-evidenced CRMs): SMIM11A,DOP1B
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 12
- Related genes and loops