- Basic information
- CohesinDB ID: CDBP00418406
- Locus: chr21-36301823-36302767
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Data sourse: GSE93080, GSE111913, ENCSR000BMY, ENCSR153HNT, GSE68388, GSE126755
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Cell type: GM12878, RT-112, K-562, Neutrophil, HuCC-T1
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 2% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.944
- Subunit: SA1,Rad21,SMC1,SA2,SMC3
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
89% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 69%,
"5_TxWk": 15%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: YBX1, PGR, SMC1A, EBF1, FOXA1, DDX5, NBN, ERG, TARDBP, ZNF384, JUNB, MYC, ONECUT1, GR, RUNX3, HIF1A, BATF3, BATF, ETV6, TP63, PAX5, GATA1, MED1, TEAD1, ELF1, ZNF121, SNAI2, TP53, ESR1, ZBTB6, ZNF22, TCF12, AR, GATA2, EGLN2, IRF4, BRD4, TCF3, RELB, EED
- Target gene symbol (double-evidenced CRMs): DOP1B,RUNX1,CBR3,SMIM11A
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 3
- Related genes and loops
- Related gene:
ENSG00000205670,
ENSG00000159216,
ENSG00000159231,
ENSG00000142197,
- Related loop:
chr21:27500000-27525000~~chr21:36275000-36300000,
chr21:34350000-34375000~~chr21:36275000-36300000,
chr21:34350000-34375000~~chr21:36300000-36325000,
chr21:35025000-35050000~~chr21:36300000-36325000,
chr21:36125000-36150000~~chr21:36300000-36325000,
chr21:36150000-36175000~~chr21:36300000-36325000,
chr21:36300000-36325000~~chr21:39175000-39200000,