- Basic information
- CohesinDB ID: CDBP00418412
- Locus: chr21-36316605-36317491
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Data sourse: GSE67783, GSE86191, ENCSR000BLS, GSE206145-NatGen2015, ENCSR153HNT
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Cell type: Fibroblast, HCT-116, Hep-G2, K-562, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.944
- Subunit: SA1,Rad21,SA2
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: TSS,TES
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
89% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 82%,
"9_Het": 8%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: ZFX, XBP1, WT1, PCBP2, HLF, ZNF580, ERG, YY1, RELA, RARA, ZNF341, MCM3, NKX2-1, ATF2, MAX, TP63, TEAD3, ZNF121, SCRT2, ZMYM3, CREB1, RCOR2, ELF3, AR, ATF7, BRD4, JUND, BCOR, NFIL3, STAG1
- Target gene symbol (double-evidenced CRMs): RUNX1,SMIM11A,DOP1B,MORC3,CBR3
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 4
- Related genes and loops
- Related gene:
ENSG00000205670,
ENSG00000159216,
ENSG00000159231,
ENSG00000142197,
ENSG00000159256,
- Related loop:
chr21:34350000-34375000~~chr21:36300000-36325000,
chr21:35025000-35050000~~chr21:36300000-36325000,
chr21:36125000-36150000~~chr21:36300000-36325000,
chr21:36150000-36175000~~chr21:36300000-36325000,
chr21:36253261-36254421~~chr21:36319310-36321320,
chr21:36259462-36261497~~chr21:36319312-36322600,
chr21:36300000-36325000~~chr21:39175000-39200000,