Deatailed information for cohesin site CDBP00418414
Check detailed explainations here
- Basic information
- CohesinDB ID: CDBP00418414
- Locus: chr21-36323820-36325021
- Data sourse: GSE67783, GSE86191, GSE132649, GSE206145, GSE206145-NatGen2015, ENCSR153HNT, GSE116344
- Cell type: RPE, T-47D, Fibroblast, RH4, HCT-116, K-562, HSPC
- DNA Sequence of binding site: UCSC hg38
- Cohesin category
- Peak occupancy ratio: 2% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.922
- Subunit: SA1,Rad21,SA2
- CTCF binding site: CTCF CTCF motif: False
- Genomic location: TSS,TES
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
- Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True
- Compartment: 89% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
-
Chromatin annotation:
"5_TxWk": 51%,
"4_Tx": 25%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2). - Co-bound Transcriptional factors: FOXO1, NFIA, TRIM25, FOXA1, HLF, RXRB, MLL4, KDM3A, HDGF, MEN1, THAP1, ZBTB44, IKZF3, MORC2, PAX5, ZNF320, SFPQ, TEAD1, SNAPC1, LMO2, OCA2, MED26, PITX3, HDAC8, ZNF561, ZNF577, E4F1, ARID5B, ZNF75A, SOX5, DEK, E2F4, ZNF528, RFX3, KMT2B, GATAD2A, JARID2, NANOG, POU5F1, BRD3, ZNF263, TOP2A, CTBP1, ZMYND11, ERF, DUX4, STAT1, ZNF134, SAP130, ERG, ZBTB21, PAX6, ZBTB8A, NFKB2, EZH1, SMARCA4, RFX1, TOP1, FOXK2, UBN1, ZNF398, RCOR1, NR2F6, DACH1, NFRKB, CD74, CEBPB, HNRNPL, CREB1, BMPR1A, GABPB1, ZHX2, ELF4, MIXL1, KLF17, GATA2, ZNF644, MXD3, FLI1, HCFC1, DRAP1, MXI1, RELB, EP400, RUVBL2, RUNX1, CEBPA, HDAC1, NKX2-2, TET2, SP5, TRIM22, SMARCC1, PRDM10, ZBTB2, ZXDC, TFDP1, SOX11, ZBTB10, ATF2, ELK1, SATB1, FOXM1, SP2, SMARCB1, GMEB1, PML, TERF1, PIAS1, SMAD1, NR1H2, C11orf30, EVI1, MBD1, STAT5A, ZNF860, IKZF5, ARID2, RBM25, AFF1, MBD2, ELL2, HMGB1, ETV4, NFATC3, CBFA2T2, MEF2B, ZNF207, CBX3, CREM, CHD2, PAF1, NFATC1, ZSCAN16, WT1, MEF2C, CREB3L1, DEAF1, NEUROD1, JUNB, TCF4, ZFP36, BATF, MAF1, SPIB, PLAG1, ZFP69B, BCL11B, KLF4, ZBTB6, MED, BCL6B, EGR2, ELF3, RBM14, ARID4B, RXR, EGLN2, ZNF366, ZBTB26, NCOR1, HSF1, SCRT1, ILF3, ZNF316, FOSL1, ZNF660, XBP1, HNF1A, KDM4B, PBX2, HNRNPK, THRB, ATF3, ZFP64, RUNX3, CBFB, ZNF273, TP63, MITF, ZNF467, MAF, INTS11, JMJD1C, ELF1, RBM39, SNAI2, KLF10, SMAD5, FUS, JUN, TAF3, CTCF, ZBTB20, MNT, LMO1, RYBP, DPF2, SIX5, IRF4, DDX20, ZNF423, ZNF350, ZNF280A, PDX1, MLX, RBPJ, TFAP2C, ZNF239, ZSCAN21, ZBTB17, ZBTB48, ZNF317, MTA2, NONO, SRF, DDX5, NBN, CHD4, PBX1, ZNF329, ONECUT1, ZNF2, HOMEZ, FOXP2, KDM4A, TSHZ1, RXRA, NKX3-1, PRDM14, LEF1, MIER3, TERF2, VDR, NR3C1, ESRRA, STAT5B, KMT2A, ZBTB11, CCAR2, TBL1XR1, KLF8, GRHL2, EBF3, KDM5A, ZBTB14, ZSCAN29, SMARCA5, NFIL3, CC2D1A, THAP11, CTNNB1, LDB1, AFF4, SOX13, POU4F2, ZNF770, ZMIZ1, ZNF18, CEBPZ, SP3, ARNT, BACH1, DAXX, ZNF48, ZEB2, HMBOX1, NFYA, PBX3, NCAPH2, ZNF10, MAFB, HMGXB4, ETV6, TEAD3, ZXDB, U2AF1, TAF7, KLF9, TBX5, USF1, BCL11A, SP1, TFAP2A, ATF7, ASH2L, CTBP2, GLIS2, PRDM6, SMC3, STAT2, MLLT1, STAG1, ZNF394, TRP47, SAFB, AGO1, MTA3, EBF1, MEIS1, MAFF, ESR2, ZNF580, ZKSCAN1, BCL3, KDM1A, KLF7, BRG1, ZNF830, ZIC2, PCGF1, GATA3, KLF15, TAL1, ZNF143, AGO2, MTA1, TP53, ZNF334, ZSCAN22, NFKB1, ZNF140, BRD2, PHF5A, KAT8, ARRB1, TBX21, EGR1, RB1, TFIIIC, RNF2, IKZF2, BRD4, JUND, SPIN1, CUX1, ZSCAN23, TBX2, ZFP42, ZNF468, PGR, FANCL, SOX2, PATZ1, SNAPC4, LEO1, UBTF, TFAP4, SIN3B, CHD7, ZNF444, MXD4, ZNF189, SMARCE1, MZF1, KLF6, NFE2L2, ZNF217, ESR1, SAP30, TP73, ZNF524, KLF1, ZNF695, SOX9, SOX4, E2F6, TRIM24, RFX5, GTF2F1, GLIS1, POU2F2, ZSCAN5D, KDM4C, ZSCAN5A, ELK4, ZMYND8, ERG2, SP4, TBP, HOXC5, OGG1, SMARCC2, ETS1, MYC, ARID1B, ZNF24, KLF12, NKX2-1, MCRS1, GABPA, STAT3, IKZF1, INO80, DNMT3B, SRSF3, EZH2, ZNF652, MRTFA, PHF8, SPI1, ZNF202, PCBP1, HDAC2, INTS13, ZNF182, GATAD2B, TAF9B, ZNF777, ZNF76, ZNF554, NFYB, ETV5, BCL6, SIN3A, ZBTB12, ERG3, MEF2A, RARA, ZNF384, NFYC, CREBBP, TAF15, ZNF35, ZNF133, ZNF518A, SMAD4, CBFA2T3, CDK8, CSNK2A1, ZEB1, ZMYM3, NCOA1, GTF3C2, RBM22, MAFK, HNF4A, NR4A1, REST, ARID1A, ZHX1, HNRNPLL, HOXA9, BCOR, FOXP1, AATF, NCOR2, CXXC4, PPARG, TBL1X, ZNF692, GTF2B, ZNF30, JDP2, ZNF574, TCF7, YY2, FOXO3, RELA, TARDBP, CHAMP1, ZNF282, SKIL, MGA, MAX, ZNF592, GFI1B, NR2F1, TCF7L2, KDM5B, NEUROG2, PKNOX1, MYOD1, T, AR, KMT2D, ZBTB16, ZNF324, HEXIM1, AHR, DMAP1, FOSL2, ZNF391, HMG20A, LCORL, HMGN3, MEIS2, SUZ12, RBFOX2, ZFHX2, SFMBT1, LYL1, ZNF274, INSM2, NFIC, ZNF362, CTCFL, PRDM1, KLF14, MECOM, HDAC3, CDX2, ZNF629, KLF5, BCLAF1, ZNF557, TRIM28, ETV1, RCOR2, MLL, HNF1B, USF2, TCF12, BAF155, EP300, GATA6, PRDM4, GLI4, SOX6, RAD51, E2F1, SMC1, TEAD4, FOXA3, ZNF175, EHMT2, EED, CHD8, BRD1, MYCN, CDK7, RUNX1T1, ID3, MLLT3, GATAD1, GMEB2, ARID3A, ASCL1, MIER1, ZNF341, ZNF84, RAD21, GRHL3, PROX1, APC, ZNF614, XRCC5, NFE2, TCF25, ZNF639, ZNF750, FEZF1, TRPS1, TFE3, HBP1, EHF, IRF1, GTF3C5, SREBF1, ZGPAT, MRTFB, ZIM3, MYF5, ATF1, PTBP1, ZNF45A, SMC1A, CBX1, SIRT6, ZNF335, ZFX, FIP1L1, ZNF534, SMAD3, PCBP2, NMYC, TWIST1, IRF2, PRPF4, NOTCH1, NCOA6, BRD9, RUNX2, CDK6, GATA4, OSR2, ZNF184, ZSCAN30, PBX4, NRF1, CHD1, SUPT5H, FOS, TGIF2, MED1, CEBPD, MYB, KDM6B, ZNF558, SCRT2, VEZF1, ZNF3, L3MBTL2, SETDB1, KLF16, NIPBL, ZBTB7A, CCNT2, PHIP, TCF3, TAF2, ZNF783, SKI, NELFA, KLF13, FOXA2, RBBP5, E2F8, ZNF600, MIER2, ZBED1, ZBTB33, CDK9, HOXB13, YY1, ASXL1, ZNF610, SP140, HIF1A, OTX2, ZNF519, ZNF449, GATA1, HAND2, TLE3, CEBPG, SP7, NR2F2, ZNF512, ZNF687, ZNF213, NFKBIZ, BHLHE40, TAF1, ZNF579, ZBTB40, ZBTB42, MYNN, NOTCH3, CLOCK, MAZ, BRCA1
- Target gene symbol (double-evidenced CRMs): RUNX1,MORC3,SMIM11A,DOP1B,CBR3
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 7
- Number of somatic mutations (non-coding): 7
- Related genes and loops
- Related gene: ENSG00000205670, ENSG00000159216, ENSG00000159231, ENSG00000142197, ENSG00000159256,
- Related loop: chr21:34350000-34375000~~chr21:36300000-36325000, chr21:34350000-34375000~~chr21:36325000-36350000, chr21:35025000-35050000~~chr21:36300000-36325000, chr21:36125000-36150000~~chr21:36300000-36325000, chr21:36125000-36150000~~chr21:36325000-36350000, chr21:36140628-36142797~~chr21:36329784-36332238, chr21:36140783-36142792~~chr21:36329776-36331881, chr21:36140789-36142775~~chr21:36329509-36332676, chr21:36140792-36142611~~chr21:36330014-36331898, chr21:36140799-36142667~~chr21:36329820-36331841, chr21:36140799-36142837~~chr21:36329790-36332543, chr21:36140822-36142823~~chr21:36329998-36331844, chr21:36140824-36142795~~chr21:36329821-36332549, chr21:36140830-36142847~~chr21:36329991-36331896, chr21:36140838-36142786~~chr21:36329955-36332030, chr21:36140848-36142815~~chr21:36329998-36332133, chr21:36140850-36142837~~chr21:36329788-36331839, chr21:36140866-36142633~~chr21:36330006-36331764, chr21:36140870-36142745~~chr21:36330021-36331732, chr21:36140871-36142703~~chr21:36330000-36331880, chr21:36150000-36175000~~chr21:36300000-36325000, chr21:36150000-36175000~~chr21:36325000-36350000, chr21:36152011-36154258~~chr21:36329911-36331790, chr21:36152093-36154114~~chr21:36329968-36331810, chr21:36152227-36154127~~chr21:36329998-36331844, chr21:36152242-36154206~~chr21:36329784-36332238, chr21:36152248-36154218~~chr21:36329821-36332549, chr21:36152272-36154246~~chr21:36329803-36332227, chr21:36152278-36154206~~chr21:36329776-36331881, chr21:36152388-36154122~~chr21:36329820-36331841, chr21:36152411-36154050~~chr21:36330018-36331884, chr21:36152478-36153914~~chr21:36329788-36331839, chr21:36152499-36154054~~chr21:36329509-36332676, chr21:36152523-36154340~~chr21:36330014-36331898, chr21:36181050-36182274~~chr21:36329784-36332238, chr21:36200000-36225000~~chr21:36325000-36350000, chr21:36208725-36210834~~chr21:36329820-36331841, chr21:36208807-36210881~~chr21:36329776-36331875, chr21:36208849-36210862~~chr21:36329821-36332549, chr21:36208896-36211059~~chr21:36329784-36332238, chr21:36225000-36250000~~chr21:36325000-36350000, chr21:36245246-36246544~~chr21:36329821-36332549, chr21:36253261-36254421~~chr21:36319310-36321320, chr21:36259462-36261497~~chr21:36319312-36322600, chr21:36300000-36325000~~chr21:39175000-39200000,
Tools:
- Assay
