- Basic information
- CohesinDB ID: CDBP00418415
- Locus: chr21-36325365-36326460
-
Data sourse: ENCSR230ZWH, GSE67783, GSE111913, ENCSR917QNE, GSE206145-NatGen2015, ENCSR153HNT, GSE165895
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Cell type: Fibroblast, RT-112, K-562, Liver, HSPC, HFFc6
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 2% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.933
- Subunit: SA1,Rad21,SA2,SMC1
-
CTCF binding site: CTCF
CTCF motif: False
- Genomic location: TSS,Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
-
Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
89% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
-
Chromatin annotation:
"5_TxWk": 56%,
"4_Tx": 17%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: FOXA1, HLF, RBFOX2, PBX2, HDGF, ATF3, ZFP64, ZNF362, ZBTB44, SMARCE1, MITF, JMJD1C, ELF1, ZNF121, E2F5, ETV1, SNAI2, MLL, HDAC8, E4F1, PYGO2, DPF2, SOX6, CREB3, DDX20, E2F1, TEAD4, KMT2B, ZNF175, GATAD2A, ID3, MTA2, ZBTB48, STAT1, HINFP, ZMYND8, DDX5, ERG, SMARCC2, MYC, SMARCA4, ARID1B, RXRA, IKZF1, NFE2, TEAD2, NR2F6, ZNF639, CEBPB, KMT2A, ZBTB11, TRPS1, NFE2L1, SPI1, ZNF664, IRF1, HDAC2, GATA2, ZNF644, FLI1, NR2C2, SMARCA5, ZNF766, ATF1, RUNX1, GTF2A2, MAFG, HDAC1, ZFX, SMARCC1, ZBTB2, ZNF384, ZNF354B, GATA4, ARNT, BACH1, TFDP1, ATF2, CBFA2T3, NR2C1, SUPT5H, CDK8, MED1, ZNF584, GMEB1, DIDO1, CEBPD, VEZF1, TAF7, L3MBTL2, ZNF22, RBM22, BCL11A, SP1, NR4A1, AFF1, ILK, MLLT1, PTTG1, NFATC3, KLF13, FOXA2, MTA3, EBF1, PAF1, ZNF600, ZSCAN16, ZBTB33, ZNF589, YY1, RELA, ZNF148, JUNB, SP140, OTX2, GATA3, TAL1, ZNF740, MAX, GATA1, MTA1, ZNF592, NR2F2, ZKSCAN8, ZNF83, NR2F1, ZNF687, PKNOX1, PTRF, ZBTB40, BRD4, JUND, SCRT1, ZSCAN23, IRF9, MEF2D, ZNF24, ZNF395
- Target gene symbol (double-evidenced CRMs): SMIM11A,DOP1B,CBR3,MORC3
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 5
- Number of somatic mutations (non-coding): 3
- Related genes and loops
- Related gene:
ENSG00000205670,
ENSG00000159231,
ENSG00000142197,
ENSG00000159256,
- Related loop:
chr21:34350000-34375000~~chr21:36300000-36325000,
chr21:34350000-34375000~~chr21:36325000-36350000,
chr21:35025000-35050000~~chr21:36300000-36325000,
chr21:36124931-36126596~~chr21:36330105-36331857,
chr21:36125000-36150000~~chr21:36300000-36325000,
chr21:36125000-36150000~~chr21:36325000-36350000,
chr21:36140628-36142797~~chr21:36329784-36332238,
chr21:36140783-36142792~~chr21:36329776-36331881,
chr21:36140789-36142775~~chr21:36329509-36332676,
chr21:36140792-36142611~~chr21:36330014-36331898,
chr21:36140799-36142667~~chr21:36329820-36331841,
chr21:36140799-36142837~~chr21:36329790-36332543,
chr21:36140822-36142823~~chr21:36329998-36331844,
chr21:36140824-36142795~~chr21:36329821-36332549,
chr21:36140830-36142847~~chr21:36329991-36331896,
chr21:36140837-36142525~~chr21:36330185-36331807,
chr21:36140838-36142724~~chr21:36330105-36331857,
chr21:36140838-36142786~~chr21:36329955-36332030,
chr21:36140848-36142815~~chr21:36329998-36332133,
chr21:36140850-36142837~~chr21:36329788-36331839,
chr21:36140851-36142527~~chr21:36330219-36331784,
chr21:36140852-36142574~~chr21:36330027-36331746,
chr21:36140857-36142570~~chr21:36330220-36331778,
chr21:36140866-36142633~~chr21:36330006-36331764,
chr21:36140870-36142745~~chr21:36330021-36331732,
chr21:36140871-36142703~~chr21:36330000-36331880,
chr21:36140877-36142726~~chr21:36330374-36331962,
chr21:36140896-36142511~~chr21:36330240-36331785,
chr21:36150000-36175000~~chr21:36300000-36325000,
chr21:36150000-36175000~~chr21:36325000-36350000,
chr21:36152011-36154258~~chr21:36329911-36331790,
chr21:36152093-36154114~~chr21:36329968-36331810,
chr21:36152185-36154228~~chr21:36330105-36331857,
chr21:36152227-36154127~~chr21:36329998-36331844,
chr21:36152242-36154206~~chr21:36329784-36332238,
chr21:36152248-36154218~~chr21:36329821-36332549,
chr21:36152272-36154246~~chr21:36329803-36332227,
chr21:36152278-36154206~~chr21:36329776-36331881,
chr21:36152287-36154113~~chr21:36330219-36331784,
chr21:36152382-36154180~~chr21:36330054-36331815,
chr21:36152388-36154122~~chr21:36329820-36331841,
chr21:36152411-36154050~~chr21:36330018-36331884,
chr21:36152478-36153914~~chr21:36329788-36331839,
chr21:36152499-36154054~~chr21:36329509-36332676,
chr21:36152523-36154340~~chr21:36330014-36331898,
chr21:36181050-36182274~~chr21:36329784-36332238,
chr21:36200000-36225000~~chr21:36325000-36350000,
chr21:36208725-36210834~~chr21:36329820-36331841,
chr21:36208807-36210881~~chr21:36329776-36331875,
chr21:36208849-36210862~~chr21:36329821-36332549,
chr21:36208896-36211059~~chr21:36329784-36332238,
chr21:36208955-36210590~~chr21:36330185-36331807,
chr21:36209099-36210510~~chr21:36330219-36331784,
chr21:36209109-36210630~~chr21:36330220-36331778,
chr21:36209128-36210456~~chr21:36330409-36331736,
chr21:36225000-36250000~~chr21:36325000-36350000,
chr21:36245123-36246662~~chr21:36330384-36331754,
chr21:36245246-36246544~~chr21:36329821-36332549,
chr21:36253261-36254421~~chr21:36319310-36321320,
chr21:36259462-36261497~~chr21:36319312-36322600,
chr21:36300000-36325000~~chr21:39175000-39200000,