- Basic information
- CohesinDB ID: CDBP00418427
- Locus: chr21-36349796-36350705
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Data sourse: GSE118494, GSE67783, GSE86191, GSE206145, ENCSR153HNT, GSE165895
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Cell type: RPE, HCT-116, IMR-90, K-562, HSPC, HFFc6
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.933
- Subunit: Mau2,SA1,Rad21,SMC1
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
89% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"4_Tx": 60%,
"5_TxWk": 28%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: FOXO1, FOSL1, CHD8, FOXA2, TOP2A, ZFX, XBP1, ZBTB17, WT1, ZSCAN5A, SMAD3, FOXA1, ZNF770, ZBTB33, DDX5, ERG3, ERG2, SRF, ZFHX2, ZNF300, YY1, RELA, ZNF384, MYC, RUNX2, ZNF362, OSR2, CHD7, ARNT, GATA3, MAX, PBX3, SUPT5H, GATA1, ZNF639, MED1, CEBPB, STAT5B, SNAI2, EGR2, PHOX2B, CTCF, RBM22, TCF12, BCL11A, JUN, MAFK, PAX8, GATA2, ZBTB26, BRD4, JUND, E2F1, MRTFB, SMC3, ZZZ3, STAG1, FOSL2
- Target gene symbol (double-evidenced CRMs): SMIM11A,DOP1B,CBR3,MORC3
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 2
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000205670,
ENSG00000159231,
ENSG00000142197,
ENSG00000159256,
- Related loop:
chr21:33550000-33575000~~chr21:36350000-36375000,
chr21:34350000-34375000~~chr21:36325000-36350000,
chr21:36125000-36150000~~chr21:36325000-36350000,
chr21:36125000-36150000~~chr21:36350000-36375000,
chr21:36150000-36175000~~chr21:36325000-36350000,
chr21:36175000-36200000~~chr21:36350000-36375000,
chr21:36200000-36225000~~chr21:36325000-36350000,
chr21:36200000-36225000~~chr21:36350000-36375000,
chr21:36225000-36250000~~chr21:36325000-36350000,
chr21:36250000-36275000~~chr21:36350000-36375000,