- Basic information
- CohesinDB ID: CDBP00418432
- Locus: chr21-36369187-36370260
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Data sourse: GSE67783, GSE86191, ENCSR000BMY, GSE25021, GSE50893
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Cell type: MCF-7, HCT-116, GM10847, GM2610, GM12878, GM2588, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.922
- Subunit: SA1,Rad21
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: non-Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
89% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"4_Tx": 82%,
"5_TxWk": 15%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: RUNX1, ZNF394, CHD8, FOXA2, CREM, TOP2A, PAF1, NME2, ZFX, ZNF317, GTF2B, XBP1, ZSCAN5A, WT1, FOXA1, ZSCAN16, ZNF770, LEO1, ZNF513, HOXB13, ARID3A, ZNF300, ERG, ZNF19, RELA, ZBTB2, ZNF384, CREBBP, JUNB, MYC, NFIC, RUNX3, PRDM1, ARNT, HIF1A, GATA3, GLYR1, MAX, SUPT5H, GATA1, ZNF143, TERF2, CDK8, MITF, VDR, CEBPB, TERF1, CREB1, EZH2, ESR1, OCA2, PKNOX1, GRHL2, EVI1, CTCF, RBM22, SPI1, BCL11A, AR, HDAC2, GATA2, IRF4, NOTCH3, BRD4, FOXP1, ZNF528, ZZZ3
- Target gene symbol (double-evidenced CRMs): DOP1B,CBR3,MORC3
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 78
- Number of somatic mutations (non-coding): 78
- Related genes and loops
- Related gene:
ENSG00000159231,
ENSG00000142197,
ENSG00000159256,
- Related loop:
chr21:33550000-33575000~~chr21:36350000-36375000,
chr21:34350000-34375000~~chr21:36375000-36400000,
chr21:36125000-36150000~~chr21:36350000-36375000,
chr21:36125000-36150000~~chr21:36375000-36400000,
chr21:36150000-36175000~~chr21:36375000-36400000,
chr21:36175000-36200000~~chr21:36350000-36375000,
chr21:36200000-36225000~~chr21:36350000-36375000,
chr21:36200000-36225000~~chr21:36375000-36400000,
chr21:36250000-36275000~~chr21:36350000-36375000,
chr21:36250000-36275000~~chr21:36375000-36400000,