Deatailed information for cohesin site CDBP00418438

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  • Basic information
  • CohesinDB ID: CDBP00418438
  • Locus: chr21-36384976-36386612
  • Data sourse: ENCSR000BLD, GSE206145-GSE177045, GSE104888, GSE72082, ENCSR000BSB, GSE126634, GSE116868, ENCSR000BLY, ENCSR404BPV, GSE111537, GSE131606, GSE108869, ENCSR330ELC, GSE25021, ENCSR917QNE, GSE165895, ENCSR000BTU, GSE67783, ENCSR000BKV, GSE86191, GSE101921, GSE206145-NatGen2015, ENCSR198ZYJ, GSE130135, ENCSR703TNG, GSE116344, GSE118494, ENCSR338DUC, ENCSR879KXD, ENCSR000BLS, GSE206145, ENCSR217ELF, ENCSR853VWZ, GSE129526, GSE111913, GSE155324, ENCSR153HNT, GSE68388, GSE50893, ENCSR000ECS, GSE38411
  • Cell type: RH4, GM10847, HSPC, Liver, HuCC-T1, RPE, GM2630, Fibroblast, Ishikawa, HeLa-S3, GM2255, IMR-90, BCBL-1, K-562, GM18486, HFFc6, GM18526, H1-hESC, SNYDER, GM18505, MB157, Lymphoblast, GM2588, SK-N-SH, RT-112, GM19099, MCF-7, GM12892, HCT-116, HEK293T, Hep-G2, Neurons-H1, A-549, HCAEC, OCI-AML-3, HAP1
  • DNA Sequence of binding site: UCSC hg38
  • Cohesin category
  • Peak occupancy ratio: 15% samples have this site.
  • Cell specificity (0: conserved, 1: cell type specific): 0.600
  • Subunit: NIPBL,SA1,Rad21,SMC1,SA2,Mau2,SMC3
  • CTCF binding site: CTCF CTCF motif: False
  • Genomic location: TSS,TES
  • 3D genome
  • TAD boundary: Boundary
  • Chromatin hubs: non-Hub
  • Hi-C loops: True Hi-ChIP loops: False ChIA-PET loops: True
  • Compartment: 89% Hi-C samples shows Compartment A
  • Cis-regulatory elements
  • Enhancer (Fantom5): non-Enhancer
  • Super enhancer (SEdb): False
  • Chromatin annotation: "5_TxWk": 28%, "1_TssA": 26%,
    Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
  • Co-bound Transcriptional factors: FOXO1, NFIA, TRIM25, NME2, FOXA1, RXRB, HDGF, THAP1, ZBTB44, IKZF3, ZNF429, MORC2, PAX5, TEAD1, ZNF121, LMO2, OCA2, MED26, ZNF561, SOX5, E2F4, ZNF528, KMT2B, GATAD2A, JARID2, NANOG, POU5F1, ZNF263, TOP2A, BRD3, CTBP1, ZMYND11, STAT1, SAP130, PAX6, ERG, ZBTB8A, NFKB2, EZH1, SMARCA4, RCOR1, NR2F6, CEBPB, HNRNPL, CREB1, GABPB1, ZHX2, MIXL1, GATA2, MXD3, SIX2, FLI1, DRAP1, MXI1, HCFC1, RELB, EP400, RUNX1, CEBPA, NKX2-2, HDAC1, SP5, SMARCC1, PRDM10, ZBTB2, TFDP1, ATF2, SP2, SMARCB1, PML, TERF1, PIAS1, SMAD1, IKZF5, ARID2, AFF1, MBD2, ELL2, HMGB1, NFATC3, CBX3, CREM, CHD2, PAF1, ZSCAN16, WT1, MEF2C, CREB3L1, NEUROD1, MCM3, ZFP36, BATF, MAF1, PLAG1, KLF4, BCL11B, MED, EGR2, ELF3, ARID4B, RXR, EGLN2, ZBTB26, HSF1, SCRT1, ILF3, FOSL1, ZNF660, XBP1, KDM4B, PBX2, HNRNPK, ATF3, ZFP64, HNRNPUL1, RUNX3, CBFB, TP63, ZSCAN4, MAF, INTS11, JMJD1C, ELF1, ZNF573, RBM39, SNAI2, KLF10, SMAD5, FUS, CTCF, TAF3, JUN, ZBTB20, MNT, LMO1, RYBP, DPF2, SIX5, IRF4, ZNF423, TFAP2C, RBPJ, ZBTB17, ZBTB48, NONO, SRF, DDX5, NBN, KDM4A, HOMEZ, FOXP2, RXRA, NR3C1, STAT5B, KMT2A, ZBTB11, CCAR2, TBL1XR1, KLF8, GRHL2, EBF3, ZKSCAN5, KDM5A, ZBTB14, NFIL3, CC2D1A, THAP11, CTNNB1, EZH2phosphoT487, SOX13, AFF4, ZNF770, ZMIZ1, SP3, ARNT, BACH1, ZNF48, PRDM9, ZEB2, NFYA, PBX3, NCAPH2, HMGXB4, TEAD3, ZXDB, U2AF1, TAF7, KLF9, USF1, BCL11A, SP1, ATF7, ASH2L, GLIS2, SMC3, STAG1, MLLT1, TRP47, AGO1, MTA3, EBF1, MEIS1, ZNF580, BCL3, ZKSCAN1, KDM1A, BRG1, ZIC2, PCGF1, TAL1, ZNF143, AGO2, TP53, ZNF334, ZSCAN22, NFKB1, BRD2, KAT8, ARRB1, TBX21, EGR1, RB1, TFIIIC, RNF2, BRD4, JUND, IRF9, PGR, FANCL, SOX2, PATZ1, LEO1, UBTF, SIN3B, ZNF444, MXD4, ZNF189, KLF6, NFE2L2, SAP30, ESR1, ZNF524, KLF1, E2F6, TRIM24, GTF2F1, GLIS1, POU2F2, ZSCAN5D, ZNF778, KDM4C, ZSCAN5A, ERG2, SP4, TBP, HOXC5, OGG1, ETS1, MYC, ARID1B, ZNF24, KLF12, NKX2-1, GABPA, MCRS1, STAT3, IKZF1, ZNF343, INO80, SRSF3, EZH2, MRTFA, PHF8, SPI1, ZNF202, PCBP1, HDAC2, INTS13, GATAD2B, ZNF76, ETV5, BCL6, SIN3A, ERG3, RARA, ZNF384, NFYC, ZNF35, TAF15, SMAD4, CDK8, CSNK2A1, ZEB1, SUPT16H, NCOA1, SREBF2, RBM22, MAFK, REST, ARID1A, ZHX1, HNRNPLL, BCOR, FOXP1, AATF, CXXC4, PPARG, TBL1X, HDAC6, ZNF692, GTF2B, ZNF574, RELA, TARDBP, CHAMP1, SKIL, MGA, MAX, GFI1B, NR2F1, TCF7L2, KDM5B, NEUROG2, PKNOX1, MYOD1, T, AR, HEXIM1, ZZZ3, DMAP1, AHR, FOSL2, E2F7, HMGN3, MEIS2, SUZ12, RBFOX2, ZFHX2, SFMBT1, CTCFL, KLF14, MECOM, ZNF736, KLF5, TRIM28, BCLAF1, RCOR2, USF2, TCF12, BAF155, EP300, E2F1, SMC1, TEAD4, FOXA3, EHMT2, EED, CHD8, BRD1, MYCN, RUNX1T1, CDK7, GATAD1, ARID3A, ASCL1, MIER1, ZNF341, RAD21, GRHL3, APC, XRCC5, ZNF614, NFE2, ZNF639, FEZF1, TFE3, IRF1, ZGPAT, NAB2, ZNF766, MRTFB, ATF1, PTBP1, SMC1A, CBX1, SIRT6, ZNF335, ZFX, FIP1L1, ZNF534, SMAD3, PCBP2, NSD2, IRF2, PRPF4, NOTCH1, RUNX2, ZSCAN30, GATA4, CDK6, ZNF184, OSR2, NRF1, ZNF708, NR2C1, SUPT5H, FOS, CHD1, MED1, KDM6B, MYB, CEBPD, SCRT2, ZNF3, L3MBTL2, SETDB1, KLF16, NIPBL, ZBTB7A, CCNT2, PHIP, TCF3, ZNF783, SKI, NELFA, KLF13, FOXA2, RBBP5, E2F8, ZNF600, MIER2, ZBED1, ZBTB33, CDK9, HOXB13, YY1, ASXL1, SP140, HIF1A, OTX2, ZNF449, GATA1, CEBPG, SP7, NCOA3, NR2F2, NFKBIZ, BHLHE40, TAF1, ZBTB40, ZBTB42, MAZ, ZNF440, BRCA1
  • Target gene symbol (double-evidenced CRMs): DOP1B,CHAF1B,CBR3,SMIM11A
  • Function elements
  • Human SNPs: .
  • Number of somatic mutations (coding): 22
  • Number of somatic mutations (non-coding): 23
  • Related genes and loops
  • Related gene: ENSG00000205670, ENSG00000159231, ENSG00000142197, ENSG00000159259,
  • Related loop: chr21:34350000-34375000~~chr21:36375000-36400000, chr21:36125000-36150000~~chr21:36375000-36400000, chr21:36140628-36142797~~chr21:36388297-36390535, chr21:36140648-36142704~~chr21:36389208-36390546, chr21:36140783-36142792~~chr21:36388547-36390538, chr21:36140808-36142792~~chr21:36389186-36390767, chr21:36140824-36142795~~chr21:36389196-36390710, chr21:36140829-36142646~~chr21:36389162-36390561, chr21:36140830-36142847~~chr21:36389185-36390513, chr21:36140835-36142753~~chr21:36388314-36390557, chr21:36140837-36142525~~chr21:36389208-36390500, chr21:36140838-36142786~~chr21:36388412-36390522, chr21:36150000-36175000~~chr21:36375000-36400000, chr21:36152221-36154286~~chr21:36388878-36390620, chr21:36152248-36154218~~chr21:36389196-36390710, chr21:36200000-36225000~~chr21:36375000-36400000, chr21:36250000-36275000~~chr21:36375000-36400000,
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