- Basic information
- CohesinDB ID: CDBP00418442
- Locus: chr21-36392384-36394412
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Data sourse: GSE206145-GSE177045, GSE67783, GSE86191, GSE116868, GSE206145, GSE206145-NatGen2015, ENCSR153HNT, GSE131606
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Cell type: MCF-7, RPE, Fibroblast, HCT-116, MB157, K-562, HSPC, DKO
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 2% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.911
- Subunit: SA1,Rad21,SMC1,SA2,Mau2
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: TSS,TES,Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: non-Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
89% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"5_TxWk": 65%,
"4_Tx": 16%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: ZNF121, ZFX, HSF1, DDX5
- Target gene symbol (double-evidenced CRMs): SMIM11A,DOP1B,CHAF1B,CBR3
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 5
- Number of somatic mutations (non-coding): 5
- Related genes and loops
- Related gene:
ENSG00000205670,
ENSG00000159231,
ENSG00000142197,
ENSG00000159259,
- Related loop:
chr21:34350000-34375000~~chr21:36375000-36400000,
chr21:36125000-36150000~~chr21:36375000-36400000,
chr21:36140628-36142797~~chr21:36388297-36390535,
chr21:36140648-36142704~~chr21:36389208-36390546,
chr21:36140783-36142792~~chr21:36388547-36390538,
chr21:36140808-36142792~~chr21:36389186-36390767,
chr21:36140824-36142795~~chr21:36389196-36390710,
chr21:36140829-36142646~~chr21:36389162-36390561,
chr21:36140830-36142847~~chr21:36389185-36390513,
chr21:36140835-36142753~~chr21:36388314-36390557,
chr21:36140837-36142525~~chr21:36389208-36390500,
chr21:36140838-36142786~~chr21:36388412-36390522,
chr21:36150000-36175000~~chr21:36375000-36400000,
chr21:36152221-36154286~~chr21:36388878-36390620,
chr21:36152248-36154218~~chr21:36389196-36390710,
chr21:36200000-36225000~~chr21:36375000-36400000,
chr21:36250000-36275000~~chr21:36375000-36400000,