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Basic information

CohesinDB ID: CDBP00418444

Locus: chr21-36399798-36400258

Data sourse: GSE206145, GSE206145-GSE177045, GSE67783, GSE86191

Cell type: MCF-7, HCT-116, HSPC, RPE

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.956

Subunit: Mau2,SA1,Rad21

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: Intragenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 89% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "5_TxWk": 60%, "4_Tx": 29%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: RELA, CHD8, ZFX, EZH2, GRHL3, XBP1, ZBTB48, ZSCAN5A, SP140, MAZ, YY1, LEO1, SUPT5H, EED

Target gene symbol (double-evidenced CRMs): CBR3,TTC3,SMIM11A,HLCS,DOP1B,CHAF1B,SIM2

Function elements

Human SNPs: .

Number of somatic mutations (coding): 4

Number of somatic mutations (non-coding): 4

Related genes and loops

Related gene: ENSG00000205670, ENSG00000159231, ENSG00000142197, ENSG00000159259, ENSG00000159263, ENSG00000159267, ENSG00000182670,

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Deatailed information for cohesin site CDBP00418444