- Basic information
- CohesinDB ID: CDBP00418449
- Locus: chr21-36411169-36411609
-
Data sourse: GSE67783, GSE86191
-
Cell type: HCT-116, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.978
- Subunit: SA1,Rad21
-
CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
-
Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
89% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
-
Chromatin annotation:
"5_TxWk": 59%,
"4_Tx": 31%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
-
Co-bound Transcriptional factors: POU5F1, TOP2A
- Target gene symbol (double-evidenced CRMs): TTC3,CHAF1B,HLCS,SIM2,SMIM11A
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 20
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000205670,
ENSG00000159259,
ENSG00000159263,
ENSG00000159267,
ENSG00000182670,
- Related loop:
chr21:34350000-34375000~~chr21:36400000-36425000,
chr21:36400000-36425000~~chr21:36500000-36525000,
chr21:36400000-36425000~~chr21:36575000-36600000,
chr21:36400000-36425000~~chr21:36600000-36625000,
chr21:36400000-36425000~~chr21:36625000-36650000,
chr21:36400000-36425000~~chr21:36675000-36700000,
chr21:36400000-36425000~~chr21:36700000-36725000,
chr21:36400000-36425000~~chr21:36850000-36875000,
chr21:36400000-36425000~~chr21:36900000-36925000,
chr21:36400000-36425000~~chr21:36925000-36950000,
chr21:36400000-36425000~~chr21:37075000-37100000,