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Basic information

CohesinDB ID: CDBP00418451

Locus: chr21-36413976-36414306

Data sourse: GSE67783, ENCSR153HNT, GSE86191

Cell type: K-562, HCT-116, HSPC

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.967

Subunit: SA1,Rad21

CTCF binding site: CTCF CTCF motif: False

Genomic location: TES,Intragenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 89% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "4_Tx": 45%, "5_TxWk": 45%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: RUNX1, TRP47, POU2F2, ZNF283, BRD1, POU5F1, MYCN, PAF1, ZFX, ZNF600, XBP1, NME2, ZBTB48, WT1, KDM4C, FOXA1, ZNF662, LEO1, SP4, HOXB13, RELA, ATF3, EZH1, PRDM1, SP140, GRHL3, ARNT, APC, TP63, ZNF143, SUPT5H, GATA1, SRSF3, PML, ZNF3, OCA2, CTCF, RBM22, SPI1, BCL11A, AR, IRF1, GATA6, NOTCH3, BRD4, MAZ, ZNF554, STAG1

Target gene symbol (double-evidenced CRMs): SMIM11A,TTC3,CHAF1B,SIM2,HLCS

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000205670, ENSG00000159259, ENSG00000159263, ENSG00000159267, ENSG00000182670,

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Deatailed information for cohesin site CDBP00418451