- Basic information
- CohesinDB ID: CDBP00418459
- Locus: chr21-36433833-36434412
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Data sourse: GSE206145-NatGen2015, GSE67783
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Cell type: Fibroblast, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.978
- Subunit: Mau2,SA1
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: TSS
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
89% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 47%,
"5_TxWk": 23%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: FOXO1, NFIA, FOXA1, RXRB, MLL4, HDGF, THAP1, PAX5, ZNF320, ZNF121, LMO2, OCA2, MED26, HDAC8, ZNF561, E4F1, SOX5, DEK, E2F4, ZNF528, KMT2B, GATAD2A, JARID2, ZNF263, BRD3, POU5F1, TOP2A, CTBP1, ERF, STAT1, ZNF134, SAP130, PAX6, ERG, ZBTB21, ZBTB8A, EZH1, SMARCA4, FOXK2, UBN1, RCOR1, CD74, NFRKB, DACH1, NR2F6, CEBPB, CREB1, EPAS1, BMPR1A, GABPB1, ZHX2, MIXL1, KLF17, GATA2, ZNF644, MXD3, SIX2, FLI1, DRAP1, NR2C2, HCFC1, MXI1, RELB, EP400, RUNX1, HDAC1, NKX2-2, CEBPA, TRIM22, SMARCC1, PRDM10, ZBTB2, ELK1, ZBTB10, TFDP1, FOXM1, SP2, SMARCB1, GMEB1, TERF1, PML, SMAD1, NR1H2, C11orf30, EVI1, STAT5A, IKZF5, OVOL3, AFF1, MBD2, ELL2, NFATC3, CBFA2T2, ZNF207, CBX3, CREM, CHD2, NFATC1, PAF1, ZSCAN16, WT1, MEF2C, NEUROD1, JUNB, ZFP36, TCF4, BATF, SPIB, PLAG1, KLF4, ZFP69B, BCL11B, ZKSCAN8, ZBTB6, EGR2, ELF3, ARID4B, RXR, ZNF366, HSF1, ZBTB26, NCOR1, ILF3, ZNF316, FOSL1, ZNF660, XBP1, PBX2, ATF3, ZC3H8, ZFP64, RUNX3, CBFB, ZNF273, TP63, MITF, BACH2, INTS11, JMJD1C, MAF, ELF1, RBM39, SNAI2, CTCF, TAF3, JUN, ZBTB20, MNT, LMO1, DPF2, RYBP, SIX5, IRF4, PDX1, RBPJ, TFAP2C, MLX, MTA2, ZBTB17, ZBTB48, ZSCAN21, ZNF317, NONO, SRF, NBN, PHB2, CHD4, ONECUT1, ZNF2, HOMEZ, FOXP2, TSHZ1, RXRA, BATF3, LEF1, TERF2, MIER3, VDR, NR3C1, ESRRA, STAT5B, KMT2A, ZBTB11, TBL1XR1, KLF8, GRHL2, SSRP1, ZSCAN29, SMARCA5, NFIL3, CC2D1A, THAP11, LDB1, AFF4, SOX13, ZNF770, ZMIZ1, ZNF18, SP3, ARNT, DAXX, BACH1, ZNF48, PRDM9, ZEB2, HMBOX1, NFYA, ETV6, PBX3, ZNF10, MAFB, HMGXB4, TEAD3, DIDO1, ZXDB, ZNF680, USF1, SP1, BCL11A, TFAP2A, ZNF479, ATF7, ASH2L, GLIS2, SMC3, STAT2, STAG1, MLLT1, STAG2, ZNF394, TRP47, SAFB, MTA3, EBF1, MAFF, ESR2, ZNF580, ZKSCAN1, BCL3, KDM1A, TCOF1, ZIC2, GATA3, TAL1, NRIP1, ZNF143, MTA1, TP53, ZNF334, ZSCAN22, NFKB1, BRD2, KAT8, TBX21, EGR1, RB1, RNF2, IKZF2, BRD4, JUND, CUX1, ZSCAN23, ZNF468, PGR, CBX5, PATZ1, UBTF, SMAD1-5, TFAP4, SIN3B, BMI1, CHD7, MXD4, ZNF189, SMARCE1, MZF1, RLF, KLF6, NFE2L2, ZNF217, ESR1, KLF1, SOX4, E2F6, TRIM24, RFX5, GTF2F1, GLIS1, POU2F2, ZSCAN5D, ZNF778, ZSCAN5A, ERG2, SP4, TBP, HOXC5, SMARCC2, ETS1, MYC, ARID1B, PHF21A, NKX2-1, GABPA, STAT3, IKZF1, ZNF343, DNMT3B, EZH2, PHF8, SPI1, HDAC2, INTS13, GATAD2B, TAF9B, NCOA2, ZNF554, NFYB, ETV5, BCL6, SIN3A, ZFP37, ERG3, MEF2A, CREBBP, ZNF384, ZNF35, RARA, NFYC, SMAD4, ZNF518A, CBFA2T3, CDK8, ZEB1, SUPT16H, NCOA1, ZNF22, MAFK, NR4A1, HNF4A, SMAD2-3, REST, ARID1A, ZHX1, HNRNPLL, BCOR, FOXP1, AATF, CXXC4, PPARG, ZNF692, GTF2B, ZNF30, ZNF574, TCF7, ZNF318, FOXO3, RELA, TARDBP, CHAMP1, ZNF282, SKIL, MGA, MAX, GFI1B, NEUROG2, TCF7L2, KDM5B, NR2F1, MYOD1, AR, ZBTB16, ZNF324, HEXIM1, ZNF395, DMAP1, AHR, FOSL2, ZNF391, HMG20A, HMGN3, SUZ12, RBFOX2, SFMBT1, ZFHX2, LYL1, ZNF90, INSM2, NFIC, ZNF274, CTCFL, PRDM1, KLF14, MECOM, HDAC3, CDX2, ZNF629, KLF5, TRIM28, BCLAF1, ETV1, RCOR2, HNF1B, USF2, TCF12, EP300, GATA6, PRDM4, GLI4, SOX6, RAD51, E2F1, SMC1, TEAD4, FOXA3, ZNF175, EED, CHD8, MYCN, RUNX1T1, ID3, GATAD1, ARID3A, ZNF341, EOMES, RAD21, GRHL3, PROX1, APC, XRCC5, ZNF614, NFE2, ZNF639, ARNTL, ZNF750, FEZF1, HES1, TFE3, EHF, IRF1, SREBF1, ZGPAT, ZNF766, MRTFB, ZIM3, MYF5, ATF1, PTBP1, SMC1A, MAFG, CBX1, SIRT6, ZNF335, ZFX, SMAD3, CBX8, TWIST1, IRF2, BRD9, RUNX2, CDK6, GATA4, OSR2, ZNF184, SMAD2, ZSCAN30, NRF1, PBX4, NR2C1, CHD1, FOS, MED1, CEBPD, MYB, VEZF1, ZNF3, L3MBTL2, SETDB1, HIF2A, KLF16, NIPBL, ZBTB7A, CCNT2, PHIP, TCF3, SKI, NELFA, ZNF283, KLF13, FOXA2, RBBP5, ZNF600, ZBED1, ZBTB33, HOXB13, ZNF589, YY1, BRCA1, SP140, HIF1A, BHLHE22, GATA1, HAND2, SP7, NCOA3, NR2F2, ZNF83, ZNF687, BHLHE40, TAF1, ZNF579, ZBTB40, ZBTB42, MYNN, CLOCK, MAZ, MEF2D, ZNF24
- Target gene symbol (double-evidenced CRMs): KCNJ15
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 0
- Related genes and loops