- Basic information
- CohesinDB ID: CDBP00418465
- Locus: chr21-36449284-36452157
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Data sourse: GSE206145-GSE177045, GSE67783, GSE86191, ENCSR000HPG, GSE206145, GSE206145-NatGen2015, GSE103477
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Cell type: MCF-7, MDM, RPE, Fibroblast, HCT-116, IMR-90, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 2% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.922
- Subunit: SA1,Rad21,SA2,Mau2,SMC3
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: TSS,Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
89% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 62%,
"14_ReprPCWk": 15%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: RUNX1, FOSL1, TRP47, BCL6, PPARG, ZNF263, CREM, TOP2A, ZFX, SMAD3, ZBTB48, CBX8, ERG3, PBX2, ERG2, BCL3, RELA, ZNF384, JUNB, ATF3, RUNX2, BMI1, SMARCA4, ARID1B, GRHL3, HIF1A, NKX2-1, ATF2, ZNF273, TAL1, MAX, STAT3, NRIP1, FOS, CBX2, VDR, CEBPB, SCRT2, EZH2, ZNF334, CTCF, JUN, ZHX2, BCL11A, BHLHE40, AR, EGR1, ATF7, FLI1, RNF2, BRD4, JUND, SCRT1, MAZ, SMC3, FOSL2
- Target gene symbol (double-evidenced CRMs): KCNJ15
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 0
- Related genes and loops