- Basic information
- CohesinDB ID: CDBP00418466
- Locus: chr21-36453766-36455047
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Data sourse: ENCSR000BTU, GSE67783, GSE72082, GSE86191, GSE98367, GSE105028, GSE101921, ENCSR054FKH, GSE206145, GSE120943
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Cell type: RPE, HCT-116, Monocytes, Hep-G2, Ishikawa, HCAEC, HSPC, Macrophage, H9-hESC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 2% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.900
- Subunit: Mau2,SA1,Rad21,SMC1
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: False
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
89% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 42%,
"7_Enh": 29%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: SOX2, XBP1, HNF1A, FOXA1, SUZ12, PBX2, RXRB, NFIC, CHD7, TP63, MITF, KLF6, RBM39, ETV1, SNAI2, ESR1, OCA2, HNF1B, USF2, JUN, TCF12, CTCF, EP300, SMC1, TEAD4, FOXA3, GATAD2A, PDX1, TFAP2C, EED, RBPJ, GLIS1, POU2F2, NANOG, BRD1, ZSCAN5D, POU5F1, CHD8, TOP2A, MYCN, ERF, ZBTB48, ZSCAN5A, ERG, ASCL1, ETS1, MYC, EOMES, RAD21, GRHL3, RXRA, GABPA, STAT3, XRCC5, IKZF1, NR2F6, NR3C1, CEBPB, ESRRA, BMPR1A, FEZF1, GABPB1, SPI1, IRF1, HDAC2, GATA2, MXD3, FLI1, ETV5, RUNX1, THAP11, ZFX, SMAD3, ZNF770, SMARCC1, RARA, RUNX2, ZNF48, PRDM9, SMAD4, FOXM1, CHD1, FOS, TEAD3, TERF1, SCRT2, USF1, HNF4A, REST, ARID1A, ZBTB7A, HNRNPLL, PHIP, BCOR, FOXP1, TCF3, STAG1, ZNF207, FOXA2, EBF1, NFATC1, WT1, ZNF580, KDM1A, YY1, RELA, JUNB, SP140, ZIC2, TAL1, MAX, CBX2, PLAG1, KLF4, NR2F2, NR2F1, TP53, PKNOX1, ZBTB6, ZNF334, ELF3, T, AR, RXR, EGR1, SCRT1, BRD4, CUX1, MAZ, AHR
- Target gene symbol (double-evidenced CRMs): .
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 0
- Related genes and loops