- Basic information
- CohesinDB ID: CDBP00418476
- Locus: chr21-36471284-36471887
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Data sourse: GSE72082, ENCSR150EFU, ENCSR000BUC, ENCSR000EAC, ENCSR000DZP, GSE138405, GSE76893, ENCSR199XBQ, ENCSR193NSH, ENCSR000BLS, GSE206145, ENCSR000BMY, ENCSR495WGO, ENCSR956LGB, ENCSR676MJK, ENCSR335RKQ, ENCSR000EDE, GSE68388, GSE126990, GSE50893, ENCSR000ECS, ENCSR481YWD
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Cell type: RPE, GM12892, GM2630, Hela-Kyoto, SNYDER, Hep-G2, GM2610, GM12878, A-549, GM12891, GM2588, GM12890, GM19238, HeLa-S3, HuCC-T1, GM18951, GM18486
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 9% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.811
- Subunit: NIPBL,SA1,Rad21,SMC1,SA2,Mau2,SMC3
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: False
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
89% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 52%,
"14_ReprPCWk": 23%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: NFIA, CBX5, HMG20A, SOX2, XBP1, FOXA1, HLF, RXRB, HDGF, ATF3, NFIC, CHD7, RUNX3, PAX5, ZNF287, ZNF736, BACH2, CDX2, MAF, BCLAF1, TRIM28, ESR1, OCA2, CTCF, JUN, TCF12, BAF155, EP300, DPF2, IRF4, ZNF528, TEAD4, FOXA3, GATAD2A, RBPJ, EED, GLIS1, POU2F2, CHD8, ZSCAN5D, MYCN, POU5F1, ZNF263, MTA2, ZBTB48, SRF, ZNF134, DDX5, NBN, SAP130, ARID3A, ZNF300, ERG, HOXC5, HNF4G, ASCL1, NFKB2, ONECUT1, MYC, SMARCA4, EOMES, HOMEZ, RAD21, RXRA, BATF3, GABPA, STAT3, XRCC5, UBN1, IKZF1, RCOR1, HNRNPH1, NR2F6, VDR, NR3C1, CEBPB, ZNF416, CREB1, ZHX2, SPI1, MIXL1, HDAC2, GATA2, FLI1, RELB, MRTFB, NFYB, ZNF554, NFIL3, BCL6, SMC1A, CEBPA, EZH2phosphoT487, ZFX, SMAD3, ZNF770, CBX8, ERG3, TET2, TWIST1, PRDM10, ZNF18, SMARCC1, MEF2A, CREBBP, ZNF384, RARA, ZNF133, ZBTB2, RUNX2, CDK6, ARNT, NRF1, PBX4, DAXX, ATF2, SMAD4, FOXM1, ETV6, ZNF10, FOS, MED1, TEAD3, PML, CEBPD, PIAS1, ZMYM3, ZNF3, SETDB1, USF1, BCL11A, MAFK, SP1, NIPBL, HNF4A, REST, ARID1A, RBM25, ATF7, TCF3, FOXP1, SMC3, MLLT1, STAG1, SKI, TRP47, TBL1X, FOXA2, CREM, EBF1, MIER2, GTF2B, WT1, BCL3, KDM1A, YY1, RELA, TARDBP, JUNB, SP140, ZFP36, ZIC2, SKIL, GATA3, BATF, MAX, CBX2, CEBPG, NR2F2, NR2F1, ZNF687, NFKB1, T, ELF3, KAT8, BRD2, TBX21, BHLHE40, AR, EGR1, ZBTB26, RNF2, IKZF2, BRD4, JUND, MAZ, AHR, FOSL2
- Target gene symbol (double-evidenced CRMs): .
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 16
- Number of somatic mutations (non-coding): 0
- Related genes and loops