- Basic information
- CohesinDB ID: CDBP00418483
- Locus: chr21-36487671-36488711
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Data sourse: ENCSR000BTQ, ENCSR230ZWH, GSE72082, GSE115250, GSE86191, ENCSR000HPG, GSE206145, GSE101921, GSE85526, GSE206145-NatGen2015, GSE68388, GSE73207, ENCSR703TNG, GSE25021, GSE50893, ENCSR917QNE
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Cell type: MCF-7, GM12892, GM2630, Fibroblast, HCT-116, RPE, HEKn, Hep-G2, SNYDER, TF-1, HCAEC, GM12891, IMR-90, Liver, TC-32, HuCC-T1
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 5% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.822
- Subunit: NIPBL,SA1,Rad21,SMC1,SA2,Mau2,SMC3
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CTCF binding site: CTCF
CTCF motif: True
- Genomic location: TSS,TES
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
89% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 57%,
"14_ReprPCWk": 20%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: RELA, TOP2A, AHR
- Target gene symbol (double-evidenced CRMs): SIM2,HLCS
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 18
- Number of somatic mutations (non-coding): 9
- Related genes and loops