- Basic information
- CohesinDB ID: CDBP00418484
- Locus: chr21-36489121-36491769
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Data sourse: GSE67783, GSE86191, GSE98367, GSE206145, GSE206145-NatGen2015, GSE120943, ENCSR153HNT, GSE83726, GSE165895
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Cell type: RPE, Fibroblast, HCT-116, Monocytes, RH4, K-562, HSPC, Macrophage, HFFc6
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 4% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.900
- Subunit: SA1,Rad21,SMC1,SA2,Mau2
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: TSS,TES
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
89% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 47%,
"14_ReprPCWk": 24%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: NFATC3, RUNX1, CHD8, PPARG, ZSCAN5D, MYCN, TOP2A, ZFX, CTBP1, XBP1, POU4F2, ZBTB48, ZSCAN5A, WT1, STAT1, TET2, SUZ12, HOXB13, ZNF596, ERG, YY1, RELA, ZNF384, NOTCH1, ASCL1, ATF3, ZNF362, SP140, GRHL3, GATA3, GABPA, MECOM, TAL1, ZNF143, PRDM14, GATA1, ZNF736, CBX2, BCL11B, MYB, ZNF544, CREB1, NR2F1, EZH2, STAG1, ESR1, SNAI2, MYOD1, CTCF, BRD2, SPI1, LMO1, AR, GATA2, FLI1, BRD4, TCF3, FOXP1, SMC3, ZFP42
- Target gene symbol (double-evidenced CRMs): SIM2,HLCS
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 14
- Number of somatic mutations (non-coding): 7
- Related genes and loops