- Basic information
- CohesinDB ID: CDBP00418485
- Locus: chr21-36492034-36493309
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Data sourse: GSE67783, GSE86191, GSE111913, GSE206145, GSE206145-NatGen2015
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Cell type: RPE, Fibroblast, HCT-116, RT-112, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.944
- Subunit: SA1,Rad21,SA2
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: TSS,TES,Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
89% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 55%,
"14_ReprPCWk": 28%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: FOXO1, PGR, CHD8, SMARCA2, MYCN, SOX2, ZFX, NME2, ZBTB48, WT1, DUX4, FOXA1, ZSCAN5A, SRF, CBX8, DDX5, HOXB13, SMARCC1, TFAP4, ERG, RELA, ZNF35, ZBTB8A, BMI1, MYC, CHD7, RAD21, ZIC2, ZFP36, GRHL3, ZSCAN4, ZNF143, CDK8, CBX2, CDX2, NR3C1, TEAD3, KLF5, SNAI2, ESR1, FEZF1, ZNF334, MRTFA, NIPBL, KLF1, MNT, AR, KLF17, TAF1, IRF1, POU2F3, FLI1, ASH2L, RNF2, ZBTB26, JUND, BRD4, FOXP1, ZNF528, MRTFB, SMC3, AHR
- Target gene symbol (double-evidenced CRMs): SIM2,HLCS
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 8
- Number of somatic mutations (non-coding): 0
- Related genes and loops