- Basic information
- CohesinDB ID: CDBP00418486
- Locus: chr21-36493632-36494257
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Data sourse: GSE67783, GSE86191, GSE206145, GSE206145-NatGen2015, ENCSR153HNT
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Cell type: RPE, Fibroblast, HCT-116, K-562, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.944
- Subunit: SA1,Rad21
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
89% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 62%,
"14_ReprPCWk": 25%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: GLIS1, ZSCAN5D, ZNF263, ZFX, XBP1, WT1, ZBTB48, ZSCAN5A, ZNF770, CBX8, TET2, ERG3, ERG2, SMARCC1, ZFHX2, ERG, YY1, RELA, JUNB, BMI1, EZH1, SMARCA4, ZNF362, BRG1, CHD7, SP140, ZFP36, ARNT, ZIC2, HIF1A, ZNF48, MAX, ZNF143, MITF, ZNF320, CBX2, PLAG1, ZNF467, SRSF3, TEAD3, ZNF141, ELF1, TRIM28, LMO2, GRHL2, CTCF, JUN, USF1, BAF155, BCL11A, MNT, REST, E2F4, RNF2, ZNF548, MAZ, SMC3, STAG1
- Target gene symbol (double-evidenced CRMs): SIM2,HLCS
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 4
- Number of somatic mutations (non-coding): 0
- Related genes and loops