- Basic information
- CohesinDB ID: CDBP00418488
- Locus: chr21-36496719-36498324
-
Data sourse: GSE67783, GSE86191, GSE98367, GSE110061, GSE206145, GSE206145-NatGen2015, GSE120943, ENCSR153HNT, GSE126755
-
Cell type: RPE, Fibroblast, HCT-116, Monocytes, K-562, Neutrophil, HSPC, Macrophage
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 3% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.911
- Subunit: SA1,Rad21,SMC1,SA2,SMC3
-
CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
-
Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
89% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
-
Chromatin annotation:
"15_Quies": 58%,
"14_ReprPCWk": 32%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
-
Co-bound Transcriptional factors: ZNF479, ZNF263, ZNF366, HSF1, ARNT, GRHL3, PCBP2, NKX2-1, HNRNPK
- Target gene symbol (double-evidenced CRMs): SIM2,HLCS
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 38
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000159263,
ENSG00000159267,
- Related loop:
chr21:34350000-34375000~~chr21:36500000-36525000,
chr21:36125000-36150000~~chr21:36500000-36525000,
chr21:36400000-36425000~~chr21:36500000-36525000,
chr21:36419354-36421097~~chr21:36503272-36505466,
chr21:36475000-36500000~~chr21:36575000-36600000,
chr21:36475000-36500000~~chr21:36725000-36750000,
chr21:36475000-36500000~~chr21:36900000-36925000,
chr21:36475000-36500000~~chr21:36925000-36950000,
chr21:36477778-36479875~~chr21:36490518-36492345,
chr21:36500000-36525000~~chr21:36600000-36625000,
chr21:36500000-36525000~~chr21:36625000-36650000,
chr21:36500000-36525000~~chr21:36675000-36700000,
chr21:36500000-36525000~~chr21:36725000-36750000,
chr21:36500000-36525000~~chr21:36825000-36850000,
chr21:36500000-36525000~~chr21:36900000-36925000,
chr21:36500000-36525000~~chr21:36925000-36950000,
chr21:36500000-36525000~~chr21:38225000-38250000,
chr21:36500000-36525000~~chr21:38250000-38275000,
chr21:36500000-36525000~~chr21:38350000-38375000,
chr21:36503141-36505653~~chr21:36926664-36928827,
chr21:36503201-36505454~~chr21:36588523-36590639,
chr21:36503201-36505454~~chr21:36926683-36929117,
chr21:36503222-36505451~~chr21:36588498-36590583,
chr21:36503227-36505444~~chr21:36588271-36590801,
chr21:36503227-36505444~~chr21:36926436-36929179,
chr21:36503239-36505647~~chr21:36926716-36929066,
chr21:36503239-36505666~~chr21:36541464-36544173,
chr21:36503239-36505666~~chr21:36588542-36590630,
chr21:36503245-36505660~~chr21:36926711-36929324,
chr21:36503265-36505404~~chr21:36588528-36590557,
chr21:36503270-36505647~~chr21:36926678-36929090,
chr21:36503272-36505466~~chr21:36588498-36590567,
chr21:36503272-36505466~~chr21:36916749-36918779,
chr21:36503272-36505466~~chr21:36926649-36929131,
chr21:36503276-36505640~~chr21:36541472-36543876,
chr21:36503276-36505640~~chr21:36588493-36590531,
chr21:36503276-36505640~~chr21:36926695-36929067,
chr21:36503288-36505684~~chr21:36541257-36544117,
chr21:36503288-36505684~~chr21:36588485-36590701,
chr21:36503288-36505684~~chr21:36629965-36632036,
chr21:36503297-36505454~~chr21:36926751-36928873,
chr21:36503297-36505649~~chr21:36541207-36544114,
chr21:36503297-36505649~~chr21:36588501-36590672,
chr21:36503297-36505649~~chr21:36853680-36855572,
chr21:36503297-36505649~~chr21:36916842-36918389,
chr21:36503297-36505649~~chr21:36926717-36929094,
chr21:36503300-36505643~~chr21:36916612-36918723,
chr21:36503300-36505643~~chr21:36926687-36928814,
chr21:36503303-36505614~~chr21:36588734-36590540,
chr21:36503304-36505537~~chr21:36588530-36590785,
chr21:36503304-36505537~~chr21:36926465-36928856,
chr21:36503313-36505627~~chr21:36926505-36928808,