Browse_each

Basic information

CohesinDB ID: CDBP00418498

Locus: chr21-36518707-36520114

Data sourse: GSE93080, ENCSR000EAC, ENCSR000DZP, GSE67783, ENCSR000BMY, ENCSR153HNT

Cell type: K-562, GM12878, HSPC

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.967

Subunit: NIPBL,SA1,Rad21,SMC1,SMC3

CTCF binding site: CTCF CTCF motif: False

Genomic location: Intragenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 92% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "15_Quies": 41%, "14_ReprPCWk": 37%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: FOXO1, NME2, XBP1, FOXA1, SUZ12, HDGF, TSC22D4, BMI1, NFIC, RUNX3, CBFB, PAX5, ZSCAN4, ELF1, TRIM28, BCLAF1, TEAD1, ZNF217, ESR1, CTCF, SND1, TCF12, EP300, DPF2, PAX8, IRF4, GTF2F1, RBPJ, EED, POU2F2, ZNF263, MYCN, RUNX1T1, MTA2, DUX4, ZNF134, DDX5, NBN, ARID3A, ZNF300, MYC, STAT3, IKZF1, KMT2A, EZH2, SPI1, GATAD2B, SIX2, SMARCA5, RELB, SMC1A, MAFG, ZFX, TRIM22, ZNF18, MEF2A, ZBTB2, CDK6, ARNT, ATF2, FOXM1, PBX3, ZNF10, ETV6, MED1, TEAD3, MYB, ZMYM3, SMAD1, C11orf30, STAT5A, MAFK, BCL11A, SP1, NIPBL, RBM25, ATF7, TCF3, FOXP1, MLLT1, STAG1, NFATC3, MEF2B, ZNF207, MTA3, EBF1, CREM, E2F8, GTF2B, MAFF, ZBED1, WT1, ZBTB33, HOXB13, BCL3, KDM1A, YY1, RELA, TARDBP, JUNB, AHR, ZFP36, HIF1A, SKIL, BATF, MAX, SPIB, ZNF143, CBX2, KLF4, ZNF592, NR2F1, ZNF687, PKNOX1, ZNF334, TBX21, BHLHE40, RB1, HSF1, IKZF2, BRD4, SCRT1, ZNF24, ZNF316

Target gene symbol (double-evidenced CRMs): KCNJ15,CHAF1B,SIM2,HLCS,CBR3

Function elements

Human SNPs: .

Number of somatic mutations (coding): 14

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000159231, ENSG00000159259, ENSG00000159263, ENSG00000159267, ENSG00000157551,

eachgene

Deatailed information for cohesin site CDBP00418498