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Basic information

CohesinDB ID: CDBP00418500

Locus: chr21-36522943-36523216

Data sourse: GSE86191

Cell type: HCT-116

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 0% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.989

Subunit: Rad21

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: TES

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 92% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "14_ReprPCWk": 44%, "15_Quies": 41%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: RUNX1, PGR, ZSCAN5D, ZNF263, MYCN, CEBPA, ZFX, ZBTB48, WT1, ZSCAN5A, FOXA1, TET2, ERG3, HOXB13, PRDM10, ERG, YY1, RELA, ATF3, MYC, CDK6, BRG1, SP140, NKX3-1, CBX2, TLE3, ZNF285, PIAS1, CTCF, BAF155, AR, GATA2, IRF4, SIX2, ASH2L, BRD4, E2F1, MAZ, SMC3, EED

Target gene symbol (double-evidenced CRMs): KCNJ15,CBR3,HLCS,SIM2,CHAF1B

Function elements

Human SNPs: .

Number of somatic mutations (coding): 6

Number of somatic mutations (non-coding): 3

Related genes and loops

Related gene: ENSG00000159231, ENSG00000159259, ENSG00000159263, ENSG00000159267, ENSG00000157551,

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Deatailed information for cohesin site CDBP00418500