- Basic information
- CohesinDB ID: CDBP00418504
- Locus: chr21-36534197-36536522
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Data sourse: ENCSR000BLD, GSE38395, GSE93080, ENCSR000EAC, ENCSR000DZP, GSE67783, GSE86191, ENCSR404BPV, GSE206145, GSE206145-NatGen2015, ENCSR000BMY, ENCSR153HNT, GSE50893
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Cell type: GM2610, B-cell, RPE, GM2630, Fibroblast, GM12890, hLCL, GM2255, K-562, GM18486, H1-hESC, SNYDER, GM12878, GM12891, GM2588, GM12892, HCT-116, Neurons-H1, GM19238, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 7% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.778
- Subunit: NIPBL,SA1,Rad21,SMC1,SA2,Mau2,SMC3
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: TES
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: non-Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
92% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"14_ReprPCWk": 52%,
"15_Quies": 22%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: PGR, SOX2, XBP1, PATZ1, FOXA1, HDGF, TSC22D4, BMI1, NFIC, RUNX3, ZBTB44, IKZF3, PRDM1, CBFB, ZNF189, PAX5, TP63, BACH2, ZNF467, ZNF629, MAF, KLF5, ELF1, BCLAF1, ZNF121, SNAI2, ZNF217, ESR1, OCA2, TP73, USF2, ZNF561, CTCF, TCF12, SND1, EP300, DPF2, IRF4, RAD51, ZNF423, ZNF528, ZNF280A, GTF2F1, RBPJ, EED, GLIS1, POU2F2, NANOG, BRD1, CHD8, POU5F1, BRD3, ZNF263, MYCN, MTA2, ZSCAN21, ZBTB17, ZNF317, ZBTB48, STAT1, SRF, NBN, ARID3A, ERG, ZBTB21, ASCL1, ZNF597, NFKB2, ZNF341, MYC, ZBTB8A, SMARCA4, ZNF2, RAD21, GRHL3, GABPA, STAT3, IKZF1, TERF2, HNRNPH1, CEBPB, CREB1, EZH2, FEZF1, ZHX2, SPI1, GATAD2B, FLI1, HCFC1, MXI1, SMARCA5, RELB, MRTFB, RUNX1, SMC1A, CEBPA, ZFX, ERG3, TRIM22, SMARCC1, PRDM10, ZNF18, MEF2A, ZNF35, OSR2, ARNT, BACH1, ATF2, PRDM9, ZEB2, PBX3, FOXM1, ETV6, CDK8, MED1, ZEB1, PML, TERF1, MYB, SCRT2, SMAD1, STAT5A, MAFK, SP1, BCL11A, NIPBL, GSPT2, REST, ATF7, ASH2L, PHIP, TCF3, FOXP1, PRDM6, SMC3, STAT2, MLLT1, STAG1, NFATC3, MEF2B, PPARG, MTA3, EBF1, CREM, SS18, E2F8, NFATC1, ZSCAN16, GTF2B, ZBED1, WT1, ZNF600, ZNF44, ZNF30, ZBTB33, TCF7, CDK9, BCL3, YY1, RELA, TARDBP, JUNB, BRG1, ZIC2, SKIL, HIF1A, GATA3, BATF, NRIP1, ZNF143, KLF4, ZNF592, NCOA3, NR2F1, ZNF687, PKNOX1, TP53, NFKB1, EGR2, BRD2, TBX21, BHLHE40, AR, TAF1, ZBTB40, ZNF324, ZBTB42, HEXIM1, RB1, IKZF2, BRD4, JUND, SCRT1, MAZ, AHR, CHD2
- Target gene symbol (double-evidenced CRMs): .
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 16
- Number of somatic mutations (non-coding): 8
- Related genes and loops