Deatailed information for cohesin site CDBP00418507

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  • Basic information
  • CohesinDB ID: CDBP00418507
  • Locus: chr21-36541555-36544346
  • Data sourse: ENCSR000BLD, GSE72082, ENCSR000BLY, GSE105028, GSE131606, ENCSR000BTU, GSE93080, ENCSR000DZP, ENCSR000EAC, GSE143937, ENCSR000BKV, GSE67783, GSE86191, GSE206145-NatGen2015, GSE106870, GSE145327, ENCSR000BLS, GSE206145, ENCSR000ECE, ENCSR000BMY, GSE38395, GSE111913, GSE155324, ENCSR153HNT, GSE50893, GSE38411
  • Cell type: GM10847, GM2610, CVB-hiPSC, GM19240, HSPC, B-cell, H9-hESC, GM2630, RPE, Fibroblast, Ishikawa, GM12890, hLCL, GM2255, BCBL-1, K-562, GM18486, DKO, GM18526, H1-hESC, SNYDER, GM18505, Lymphoblast, GM12878, GM12891, GM2588, SK-N-SH, GM19239, RT-112, GM19193, GM19099, GM12892, HCT-116, Hep-G2, GM19238, GM18951
  • DNA Sequence of binding site: UCSC hg38
  • Cohesin category
  • Peak occupancy ratio: 16% samples have this site.
  • Cell specificity (0: conserved, 1: cell type specific): 0.600
  • Subunit: NIPBL,SA1,Rad21,SMC1,SA2,Mau2,SMC3
  • CTCF binding site: CTCF CTCF motif: False
  • Genomic location: TSS
  • 3D genome
  • TAD boundary: Boundary
  • Chromatin hubs: non-Hub
  • Hi-C loops: True Hi-ChIP loops: False ChIA-PET loops: True
  • Compartment: 92% Hi-C samples shows Compartment A
  • Cis-regulatory elements
  • Enhancer (Fantom5): non-Enhancer
  • Super enhancer (SEdb): True
  • Chromatin annotation: "13_ReprPC": 35%, "14_ReprPCWk": 33%,
    Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
  • Co-bound Transcriptional factors: FOSL1, ZNF621, MEIS2, XBP1, KDM4B, FOXA1, SUZ12, RING1B, PBX2, HDGF, ATF3, NFIC, BMI1, ZBTB5, RUNX3, CHD7, PRDM1, ZNF444, CBFB, PAX5, TP63, ZSCAN4, ZNF736, CDC5L, ZNF586, KLF5, BCLAF1, ELF1, ZNF283, ZNF217, ESR1, OCA2, SMAD5, PITX3, ZIK1, USF2, CTCF, JUN, TCF12, SND1, E4F1, EP300, MNT, ZNF157, GATA6, BAF155, DPF2, PAX8, RYBP, E2F6, TRIM24, IRF4, GLI4, SOX6, ZNF407, ZNF211, RAD51, ZNF512B, ZNF776, TEAD4, ZNF175, GTF2F1, EHMT2, PLRG1, EED, RBPJ, YBX1, TFAP2C, JARID2, POU2F2, NANOG, PDX1, BRD1, ZNF263, ZNF239, RUNX1T1, MYCN, POU5F1, CTBP1, ZSCAN21, ZBTB1, ZBTB48, ZSCAN5A, ASH1L, MTA2, NONO, SRF, ZBTB17, DDX5, NBN, ERG2, PHB2, ARID3A, TBP, HNF4G, ERG, SAP130, ASCL1, OGG1, ZNF341, MCM5, MYC, SMARCA4, RFX1, KDM4A, RAD21, ONECUT1, GRHL3, RXRA, FOXK2, GABPA, STAT3, NKX3-1, ZNF398, IKZF1, PRDM14, RCOR1, ZNF639, NFE2, ARNTL, NR3C1, ESRRA, CREB1, EZH2, ARHGAP35, BMPR1A, EBF3, HES1, SPI1, IRF1, ZNF257, HDAC2, SSRP1, GATA2, GATAD2B, HCFC1, ZNF785, MXI1, SMARCA5, DRAP1, ZNF766, RELB, HEXIM1-CDK9, MRTFB, HCFC1R1, NCOA2, ZNF316, SALL2, RUNX1, SMC1A, BCL6, HDAC1, EZH2phosphoT487, ZNF707, CRY1, SIN3A, ZFX, ZNF534, AFF4, SMAD3, TET2, ZNF473, CBX8, MCM2, TRIM22, SMARCC1, PRDM10, ZNF18, TWIST1, ZBTB2, ZNF384, CREBBP, TAF15, BRD9, GATA4, OSR2, ZNF184, ARNT, NFIB, BACH1, NRF1, ATF2, ZNF48, ETV6, PBX3, NCAPH2, FOS, FOXM1, CBFA2T3, MAFB, MED1, ZEB1, PML, SCRT2, ZMYM3, SMAD1, PIAS1, KLF9, MAFG, C11orf30, USF1, BCL11A, NIPBL, SP1, HNF4A, FOXA2, MAFK, ARID2, REST, ZBTB7A, RBM25, ATF7, POU2F3, ASH2L, ZNF548, CTBP2, BCOR, FOXP1, SALL1, TCF3, AATF, SMC3, NCOR2, STAG1, MLLT1, NFATC3, TRP47, NCOA4, MEF2B, CBFA2T2, TBL1X, ZNF207, MTA3, EBF1, CREM, E2F8, HDAC6, RBBP5, GTF2B, WT1, ZBED1, CHD2, FOXF1, MAFF, ZNF662, ZBTB33, ESR2, CDK9, HOXB13, ZKSCAN1, BCL3, KDM1A, YY1, RELA, ZNF318, TARDBP, ZNF148, JUNB, BRG1, ZNF521, MCM3, SP140, ZFP36, SKIL, PCGF1, HIF1A, ZNF311, GATA3, BATF, MAF1, MAX, NRIP1, GATA1, ZNF143, CBX2, PLAG1, ZNF592, NCOA3, NR2F2, ZNF544, NR2F1, ZNF791, KDM5B, ZNF687, PKNOX1, TP53, ZNF645, ZNF547, ZNF334, BCL6B, MYOD1, PHOX2B, TBX21, BHLHE40, AR, TAF1, ZBTB40, RXR, EGLN2, EGR1, RB1, TFIIIC, HSF1, RNF2, IKZF2, BRD4, HEXIM1, JUND, CLOCK, MAZ, ZNF24, AHR
  • Target gene symbol (double-evidenced CRMs): .
  • Function elements
  • Human SNPs: .
  • Number of somatic mutations (coding): 25
  • Number of somatic mutations (non-coding): 13
  • Related genes and loops
  • Related gene:
  • Related loop: chr21:36503239-36505666~~chr21:36541464-36544173, chr21:36503276-36505640~~chr21:36541472-36543876, chr21:36503288-36505684~~chr21:36541257-36544117, chr21:36503297-36505649~~chr21:36541207-36544114, chr21:36503483-36505671~~chr21:36541462-36543965, chr21:36503500-36505460~~chr21:36542054-36543828, chr21:36503508-36505467~~chr21:36542130-36543832, chr21:36503560-36505447~~chr21:36542235-36543689, chr21:36503767-36505530~~chr21:36541813-36544170, chr21:36503774-36505468~~chr21:36542261-36543875, chr21:36503775-36505445~~chr21:36541324-36544050, chr21:36503775-36505593~~chr21:36542212-36543904, chr21:36503783-36505447~~chr21:36542194-36544140, chr21:36503791-36505388~~chr21:36541297-36543916, chr21:36525000-36550000~~chr21:41350000-41375000,
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