- Basic information
- CohesinDB ID: CDBP00418508
- Locus: chr21-36545871-36546537
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Data sourse: GSE206145, GSE206145-NatGen2015, ENCSR230ZWH, ENCSR917QNE
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Cell type: RPE, Liver, Fibroblast
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.967
- Subunit: Mau2,Rad21
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: TSS
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: non-Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
92% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"14_ReprPCWk": 58%,
"13_ReprPC": 17%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: FOSL1, ZNF621, MEIS2, XBP1, KDM4B, FOXA1, SUZ12, RING1B, PBX2, HDGF, ATF3, NFIC, BMI1, ZBTB5, RUNX3, CHD7, PRDM1, ZNF444, CBFB, PAX5, TP63, ZSCAN4, ZNF736, CDC5L, ZNF586, KLF5, BCLAF1, ELF1, ZNF283, ZNF217, ESR1, OCA2, SMAD5, PITX3, ZIK1, USF2, CTCF, JUN, TCF12, SND1, E4F1, EP300, MNT, ZNF157, GATA6, BAF155, DPF2, PAX8, RYBP, E2F6, TRIM24, IRF4, GLI4, SOX6, ZNF407, ZNF211, RAD51, ZNF512B, ZNF776, TEAD4, ZNF175, GTF2F1, EHMT2, PLRG1, EED, RBPJ, YBX1, TFAP2C, JARID2, POU2F2, NANOG, PDX1, BRD1, ZNF263, ZNF239, RUNX1T1, MYCN, POU5F1, CTBP1, ZSCAN21, ZBTB1, ZBTB48, ZSCAN5A, ASH1L, MTA2, NONO, SRF, ZBTB17, DDX5, NBN, ERG2, PHB2, ARID3A, TBP, HNF4G, ERG, SAP130, ASCL1, OGG1, ZNF341, MCM5, MYC, SMARCA4, RFX1, KDM4A, RAD21, ONECUT1, GRHL3, RXRA, FOXK2, GABPA, STAT3, NKX3-1, ZNF398, IKZF1, PRDM14, RCOR1, ZNF639, NFE2, ARNTL, NR3C1, ESRRA, CREB1, EZH2, ARHGAP35, BMPR1A, EBF3, HES1, SPI1, IRF1, ZNF257, HDAC2, SSRP1, GATA2, GATAD2B, HCFC1, ZNF785, MXI1, SMARCA5, DRAP1, ZNF766, RELB, HEXIM1-CDK9, MRTFB, HCFC1R1, NCOA2, ZNF316, SALL2, RUNX1, SMC1A, BCL6, HDAC1, EZH2phosphoT487, ZNF707, CRY1, SIN3A, ZFX, ZNF534, AFF4, SMAD3, TET2, ZNF473, CBX8, MCM2, TRIM22, SMARCC1, PRDM10, ZNF18, TWIST1, ZBTB2, ZNF384, CREBBP, TAF15, BRD9, GATA4, OSR2, ZNF184, ARNT, NFIB, BACH1, NRF1, ATF2, ZNF48, ETV6, PBX3, NCAPH2, FOS, FOXM1, CBFA2T3, MAFB, MED1, ZEB1, PML, SCRT2, ZMYM3, SMAD1, PIAS1, KLF9, MAFG, C11orf30, USF1, BCL11A, NIPBL, SP1, HNF4A, FOXA2, MAFK, ARID2, REST, ZBTB7A, RBM25, ATF7, POU2F3, ASH2L, ZNF548, CTBP2, BCOR, FOXP1, SALL1, TCF3, AATF, SMC3, NCOR2, STAG1, MLLT1, NFATC3, TRP47, NCOA4, MEF2B, CBFA2T2, TBL1X, ZNF207, MTA3, EBF1, CREM, E2F8, HDAC6, RBBP5, GTF2B, WT1, ZBED1, CHD2, FOXF1, MAFF, ZNF662, ZBTB33, ESR2, CDK9, HOXB13, ZKSCAN1, BCL3, KDM1A, YY1, RELA, ZNF318, TARDBP, ZNF148, JUNB, BRG1, ZNF521, MCM3, SP140, ZFP36, SKIL, PCGF1, HIF1A, ZNF311, GATA3, BATF, MAF1, MAX, NRIP1, GATA1, ZNF143, CBX2, PLAG1, ZNF592, NCOA3, NR2F2, ZNF544, NR2F1, ZNF791, KDM5B, ZNF687, PKNOX1, TP53, ZNF645, ZNF547, ZNF334, BCL6B, MYOD1, PHOX2B, TBX21, BHLHE40, AR, TAF1, ZBTB40, RXR, EGLN2, EGR1, RB1, TFIIIC, HSF1, RNF2, IKZF2, BRD4, HEXIM1, JUND, CLOCK, MAZ, ZNF24, AHR
- Target gene symbol (double-evidenced CRMs): .
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 7
- Number of somatic mutations (non-coding): 7
- Related genes and loops
- Related gene:
- Related loop:
chr21:34350000-34375000~~chr21:36550000-36575000,
chr21:36250000-36275000~~chr21:36550000-36575000,
chr21:36503239-36505666~~chr21:36541464-36544173,
chr21:36503276-36505640~~chr21:36541472-36543876,
chr21:36503288-36505684~~chr21:36541257-36544117,
chr21:36503297-36505649~~chr21:36541207-36544114,
chr21:36503483-36505671~~chr21:36541462-36543965,
chr21:36503500-36505460~~chr21:36542054-36543828,
chr21:36503508-36505467~~chr21:36542130-36543832,
chr21:36503560-36505447~~chr21:36542235-36543689,
chr21:36503767-36505530~~chr21:36541813-36544170,
chr21:36503774-36505468~~chr21:36542261-36543875,
chr21:36503775-36505445~~chr21:36541324-36544050,
chr21:36503775-36505593~~chr21:36542212-36543904,
chr21:36503783-36505447~~chr21:36542194-36544140,
chr21:36503791-36505388~~chr21:36541297-36543916,
chr21:36525000-36550000~~chr21:41350000-41375000,