- Basic information
- CohesinDB ID: CDBP00418509
- Locus: chr21-36547503-36548857
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Data sourse: GSE206145-NatGen2015, GSE67783, ENCSR153HNT, GSE86191
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Cell type: K-562, Fibroblast, HCT-116, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.956
- Subunit: SA1,Rad21,SA2
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: TSS,Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: non-Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
92% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"14_ReprPCWk": 49%,
"13_ReprPC": 21%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: TRP47, MYCN, SIRT6, SOX2, ZFX, ZBTB48, WT1, ZSCAN5A, FOXA1, TET2, YY1, RELA, ATF3, ONECUT1, MYC, BRG1, SP140, GRHL3, ZFP36, RXRA, TP63, HNRNPH1, CBX2, ELF1, CREB1, EZH2, ESR1, CTCF, SP1, EP300, SPI1, HNF4A, AR, HEXIM1, HSF1, MXI1, HNRNPLL, BRD4, MAZ, AATF, ZNF528, NCOR2, STAG1
- Target gene symbol (double-evidenced CRMs): .
- Function elements
- Human SNPs: Heel_bone_mineral_density
- Number of somatic mutations (coding): 13
- Number of somatic mutations (non-coding): 4
- Related genes and loops
- Related gene:
- Related loop:
chr21:34350000-34375000~~chr21:36550000-36575000,
chr21:36250000-36275000~~chr21:36550000-36575000,
chr21:36503239-36505666~~chr21:36541464-36544173,
chr21:36503276-36505640~~chr21:36541472-36543876,
chr21:36503288-36505684~~chr21:36541257-36544117,
chr21:36503297-36505649~~chr21:36541207-36544114,
chr21:36503483-36505671~~chr21:36541462-36543965,
chr21:36503500-36505460~~chr21:36542054-36543828,
chr21:36503508-36505467~~chr21:36542130-36543832,
chr21:36503560-36505447~~chr21:36542235-36543689,
chr21:36503767-36505530~~chr21:36541813-36544170,
chr21:36503774-36505468~~chr21:36542261-36543875,
chr21:36503775-36505445~~chr21:36541324-36544050,
chr21:36503775-36505593~~chr21:36542212-36543904,
chr21:36503783-36505447~~chr21:36542194-36544140,
chr21:36503791-36505388~~chr21:36541297-36543916,
chr21:36525000-36550000~~chr21:41350000-41375000,