- Basic information
- CohesinDB ID: CDBP00418510
- Locus: chr21-36549263-36549881
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Data sourse: GSE67783, GSE120943, ENCSR153HNT, GSE86191
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Cell type: K-562, Monocytes, HCT-116, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.956
- Subunit: SA1,Rad21,SMC1
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: non-Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
92% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"14_ReprPCWk": 52%,
"15_Quies": 17%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: FOXO1, PGR, FANCL, SOX2, NME2, FOXA1, ATF3, NFIC, RUNX3, CBFB, ZSCAN4, ZNF467, JMJD1C, MYOG, ZNF573, ESR1, MLL, OCA2, HDAC8, USF2, CTCF, JUN, TCF12, BAF155, EP300, KLF1, E2F6, IRF4, E2F1, TEAD4, ZNF175, TFAP2C, NANOG, CHD8, BRD1, ZSCAN5D, ZNF263, POU5F1, TOP2A, MYCN, ID3, ZBTB17, ZBTB48, ZSCAN5A, STAT1, DUX4, SRF, ZNF134, MLLT3, ERG, ZNF341, MYC, RAD21, GRHL3, RXRA, STAT3, PRDM14, DNMT3B, NR3C1, CEBPB, KMT2A, EZH2, FEZF1, GRHL2, SPI1, KLF17, ZNF257, ZNF146, SIX2, FLI1, MRTFB, ZIM3, ZNF554, RUNX1, CEBPA, EZH2phosphoT487, LDB1, CRY1, ZNF335, ZFX, TET2, SMARCC1, PRDM10, TWIST1, ZNF384, RUNX2, GATA4, ARNT, PBX3, ZNF10, FOS, MED1, ZEB1, ZNF558, MYB, SCRT2, ZMYM3, ZNF3, USF1, BCL11A, ZNF479, ZBTB7A, RBM25, ATF7, ASH2L, PHIP, PRDM6, SMC3, STAG1, SKI, SS18, ZNF692, WT1, ESR2, MEF2C, CDK9, KDM1A, YY1, RELA, JUNB, BRG1, SP140, ZFP36, HIF1A, GATA3, BATF, MAX, ZNF143, GATA1, CBX2, ZFP69B, ZNF592, SP7, ZNF768, PKNOX1, ZNF334, MYOD1, BRD2, BHLHE40, AR, PAX3-FOXO1, ZBTB42, HSF1, BRD4, JUND, SCRT1, MAZ, AHR, FOSL2
- Target gene symbol (double-evidenced CRMs): .
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 16
- Number of somatic mutations (non-coding): 0
- Related genes and loops