- Basic information
- CohesinDB ID: CDBP00418517
- Locus: chr21-36566551-36567815
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Data sourse: GSE67783, ShirahigeLab, ShirahigeLab-NatGen2015, ENCSR153HNT, GSE130135
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Cell type: K-562, Fibroblast, HSPC, HEK293T
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 3% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.944
- Subunit: NIPBL,SA1,Rad21,SA2,Mau2
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
92% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"14_ReprPCWk": 39%,
"15_Quies": 30%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: ZNF426, SMARCA2, ZNF660, ZSCAN5C, ZNF101, FOXA1, PATZ1, ZNF596, ZNF529, ATF3, ZFP64, ZBTB44, PRDM1, IKZF3, ZNF189, MZF1, ZSCAN4, ZNF467, ZNF629, KLF5, ELF1, TRIM28, ZNF121, KLF10, ZNF624, ESR1, OCA2, ZNF561, CTCF, JUN, ZNF577, PRDM4, ZNF423, ZNF528, KLF3, GLIS1, POU2F2, ZSCAN5D, BRD3, ZNF263, MYCN, ZNF778, CTBP1, ZBTB17, ZBTB48, ZSCAN5A, SRF, ZNF488, ZNF134, SP4, ZBTB21, ZBTB8A, ZNF341, ONECUT1, GRHL3, APC, STAT3, ZNF398, CREB1, EZH2, GRHL2, FEZF1, MRTFA, ZNF664, ZNF257, SIX2, FLI1, MRTFB, MYF5, EZH2phosphoT487, ZFX, ZBTB12, ZNF770, ZNF513, TWIST1, PRDM10, SMARCC1, ZNF18, ZNF35, ZSCAN30, OSR2, ZNF184, DAXX, ARNT, ATF2, ZEB2, ZNF518A, ZNF10, SNRNP70, ZXDB, ZNF558, NUP98-HOXA9, BCL11A, ZNF479, GLI2, OVOL3, ZNF605, HOXA9, PHIP, SALL1, PRDM6, SMC3, NCOR2, ZNF34, STAG1, CXXC4, ZNF394, MEIS1, SS18, ZNF600, ZNF692, ZSCAN16, WT1, ZNF30, ESR2, ZNF574, ZNF580, YY1, RELA, ZNF510, ZNF610, ZIC2, ZNF449, ZNF143, ZFP69B, SP7, GFI1B, TCF7L2, PKNOX1, ZBTB6, ZNF213, ZNF645, MYOD1, BRD2, ZNF843, AR, ZNF324, ZBTB42, NCOR1, BRD4, MAZ, ZSCAN23, ZNF24, AHR
- Target gene symbol (double-evidenced CRMs): DOP1B
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 7
- Number of somatic mutations (non-coding): 0
- Related genes and loops