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Basic information

CohesinDB ID: CDBP00418519

Locus: chr21-36570859-36571195

Data sourse: GSE67783, GSE111913, ENCSR153HNT

Cell type: K-562, RT-112, HSPC

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.967

Subunit: SA1,SA2

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: Intragenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: False ChIA-PET loops: True

Compartment: 92% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "14_ReprPCWk": 47%, "15_Quies": 40%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: NFATC3, GLIS1, PGR, CHD8, POU2F2, CEBPA, MYCN, ZSCAN5C, ZNF263, ZSCAN5D, ZFX, ZNF600, ZNF692, GTF2B, ZBTB17, ZBTB48, PATZ1, XBP1, ZSCAN5A, MAFF, CBX8, ERG3, SUZ12, ERG2, PBX2, ZNF580, TWIST1, PRDM10, ZNF18, YY1, RELA, ZNF224, ZBTB8A, ZNF341, ATF3, MYC, BRG1, ZFP64, ZNF184, ZBTB44, SP3, GRHL3, HIF1A, ARNT, ZEB2, CBX2, CEBPG, CEBPB, SP7, NR3C1, TEAD1, EZH2, TP53, PKNOX1, ZNF41, ZNF334, ZNF561, BRD2, CTCF, AR, ZBTB42, SIX2, FLI1, RNF2, NOTCH3, BRD4, PHIP, ZNF766, ZNF528, MAZ, PRDM6, SMC3, ZNF34

Target gene symbol (double-evidenced CRMs): DOP1B

Function elements

Human SNPs: .

Number of somatic mutations (coding): 4

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000142197,

eachgene

Deatailed information for cohesin site CDBP00418519