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Basic information

CohesinDB ID: CDBP00418521

Locus: chr21-36575350-36575709

Data sourse: ENCSR879KXD, GSE73207

Cell type: K-562, TF-1

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.978

Subunit: SMC3,Rad21

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: TSS

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 92% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "15_Quies": 48%, "14_ReprPCWk": 42%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: FOSL1, PGR, FANCL, FOXA1, PBX2, HDGF, LYL1, ATF3, THAP1, ATF4, SMARCE1, PAX5, JMJD1C, TRIM28, RBM39, CTCF, TCF12, ZNF577, EP300, KLF1, LMO1, TRIM24, SOX6, E2F4, ZNF528, TEAD4, ZNF175, TFAP2C, RBPJ, CHD8, MYCN, TOP2A, CTBP1, ZNF317, DUX4, ZBTB48, STAT1, SRF, TBP, ERG, ZBTB21, SMARCA4, ARID1B, GABPA, STAT3, IKZF1, RCOR1, NFE2, NR2F6, ZNF750, NR3C1, ESRRA, CEBPB, EZH2, SPI1, HDAC2, GATA2, ZNF644, SIX2, FLI1, RELB, RUNX1, CBX1, SMC1A, HDAC1, LDB1, ZFX, TET2, PRDM10, ZNF384, OSR2, ARNT, ATF2, CBFA2T3, PML, CEBPD, MYB, ZMYM3, SMAD1, STAT5A, KLF16, BCL11A, ZBTB7A, RBM25, ATF7, BCOR, TCF3, SMC3, STAG1, TRP47, CBFA2T2, TBL1X, CREM, ZNF692, ZSCAN16, ZNF30, WT1, HOXB13, KDM1A, ZNF19, SP140, ZIC2, HIF1A, TAL1, MAX, GATA1, ZNF143, CEBPG, SP7, NR2F2, ZNF83, TCF7L2, AR, HSF1, NCOR1, RNF2, BRD4, ZNF24, ADNP

Target gene symbol (double-evidenced CRMs): KCNJ6,CBR3,SIM2,HLCS,CHAF1B,DOP1B

Function elements

Human SNPs: .

Number of somatic mutations (coding): 4

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000159231, ENSG00000142197, ENSG00000159259, ENSG00000159263, ENSG00000159267, ENSG00000157542,

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Deatailed information for cohesin site CDBP00418521