- Basic information
- CohesinDB ID: CDBP00418522
- Locus: chr21-36576412-36577230
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Data sourse: ShirahigeLab, GSE67783, GSE86191
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Cell type: RPE, HCT-116, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.967
- Subunit: SA1,Rad21
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: TSS,TES
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
92% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"15_Quies": 46%,
"14_ReprPCWk": 46%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: FOSL1, PGR, FANCL, FOXA1, PBX2, HDGF, LYL1, ATF3, THAP1, ATF4, SMARCE1, PAX5, JMJD1C, TRIM28, RBM39, CTCF, TCF12, ZNF577, EP300, KLF1, LMO1, TRIM24, SOX6, E2F4, ZNF528, TEAD4, ZNF175, TFAP2C, RBPJ, CHD8, MYCN, TOP2A, CTBP1, ZNF317, DUX4, ZBTB48, STAT1, SRF, TBP, ERG, ZBTB21, SMARCA4, ARID1B, GABPA, STAT3, IKZF1, RCOR1, NFE2, NR2F6, ZNF750, NR3C1, ESRRA, CEBPB, EZH2, SPI1, HDAC2, GATA2, ZNF644, SIX2, FLI1, RELB, RUNX1, CBX1, SMC1A, HDAC1, LDB1, ZFX, TET2, PRDM10, ZNF384, OSR2, ARNT, ATF2, CBFA2T3, PML, CEBPD, MYB, ZMYM3, SMAD1, STAT5A, KLF16, BCL11A, ZBTB7A, RBM25, ATF7, BCOR, TCF3, SMC3, STAG1, TRP47, CBFA2T2, TBL1X, CREM, ZNF692, ZSCAN16, ZNF30, WT1, HOXB13, KDM1A, ZNF19, SP140, ZIC2, HIF1A, TAL1, MAX, GATA1, ZNF143, CEBPG, SP7, NR2F2, ZNF83, TCF7L2, AR, HSF1, NCOR1, RNF2, BRD4, ZNF24, ADNP
- Target gene symbol (double-evidenced CRMs): HLCS,KCNJ6,CBR3,DOP1B,SIM2,CHAF1B
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 3
- Related genes and loops
- Related gene:
ENSG00000159231,
ENSG00000142197,
ENSG00000159259,
ENSG00000159263,
ENSG00000159267,
ENSG00000157542,
- Related loop:
chr21:34350000-34375000~~chr21:36550000-36575000,
chr21:36125000-36150000~~chr21:36575000-36600000,
chr21:36175000-36200000~~chr21:36575000-36600000,
chr21:36250000-36275000~~chr21:36550000-36575000,
chr21:36400000-36425000~~chr21:36575000-36600000,
chr21:36425000-36450000~~chr21:36575000-36600000,
chr21:36475000-36500000~~chr21:36575000-36600000,
chr21:36575000-36600000~~chr21:36675000-36700000,
chr21:36575000-36600000~~chr21:36725000-36750000,
chr21:36575000-36600000~~chr21:36850000-36875000,
chr21:36575000-36600000~~chr21:36900000-36925000,
chr21:36575000-36600000~~chr21:37650000-37675000,