- Basic information
- CohesinDB ID: CDBP00418523
- Locus: chr21-36583668-36584068
-
Data sourse: GSE206145-NatGen2015, GSE86191
-
Cell type: Fibroblast, HCT-116
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 0% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.978
- Subunit: SA1,Rad21
-
CTCF binding site: CTCF
CTCF motif: False
- Genomic location: TSS,TES
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
-
Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
92% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
-
Chromatin annotation:
"15_Quies": 47%,
"14_ReprPCWk": 45%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
-
Co-bound Transcriptional factors: NCOA3, MYCN, PBX2, GRHL3, PKNOX1, BRD4, WT1, CTCF
- Target gene symbol (double-evidenced CRMs): HLCS,KCNJ6,DOP1B,CBR3,CHAF1B,SIM2
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 2
- Related genes and loops
- Related gene:
ENSG00000159231,
ENSG00000142197,
ENSG00000159259,
ENSG00000159263,
ENSG00000159267,
ENSG00000157542,
- Related loop:
chr21:36125000-36150000~~chr21:36575000-36600000,
chr21:36175000-36200000~~chr21:36575000-36600000,
chr21:36400000-36425000~~chr21:36575000-36600000,
chr21:36418841-36421262~~chr21:36588530-36590785,
chr21:36418853-36423205~~chr21:36588271-36590801,
chr21:36419158-36421245~~chr21:36588474-36590657,
chr21:36419182-36421107~~chr21:36588390-36590623,
chr21:36419194-36421140~~chr21:36588734-36590540,
chr21:36419201-36421142~~chr21:36588485-36590701,
chr21:36419216-36421134~~chr21:36588498-36590583,
chr21:36419245-36420874~~chr21:36588511-36590472,
chr21:36419258-36420992~~chr21:36588860-36590466,
chr21:36419274-36421021~~chr21:36588675-36590309,
chr21:36419280-36421083~~chr21:36588665-36590475,
chr21:36419354-36421097~~chr21:36588498-36590567,
chr21:36419356-36420914~~chr21:36588710-36590304,
chr21:36421367-36423313~~chr21:36588390-36590623,
chr21:36421381-36423343~~chr21:36588528-36590557,
chr21:36421400-36423189~~chr21:36588493-36590531,
chr21:36421419-36423290~~chr21:36588485-36590701,
chr21:36421424-36423153~~chr21:36588511-36590472,
chr21:36421453-36423350~~chr21:36588498-36590567,
chr21:36421457-36423277~~chr21:36588417-36590557,
chr21:36421469-36423169~~chr21:36588501-36590672,
chr21:36421646-36423206~~chr21:36588699-36590235,
chr21:36421690-36423243~~chr21:36588716-36590491,
chr21:36421773-36423174~~chr21:36588574-36590548,
chr21:36425000-36450000~~chr21:36575000-36600000,
chr21:36475000-36500000~~chr21:36575000-36600000,
chr21:36478462-36479768~~chr21:36588710-36590304,
chr21:36503201-36505454~~chr21:36588523-36590639,
chr21:36503222-36505451~~chr21:36588498-36590583,
chr21:36503227-36505444~~chr21:36588271-36590801,
chr21:36503239-36505666~~chr21:36588542-36590630,
chr21:36503265-36505404~~chr21:36588528-36590557,
chr21:36503272-36505466~~chr21:36588498-36590567,
chr21:36503276-36505640~~chr21:36588493-36590531,
chr21:36503288-36505684~~chr21:36588485-36590701,
chr21:36503297-36505649~~chr21:36588501-36590672,
chr21:36503303-36505614~~chr21:36588734-36590540,
chr21:36503304-36505537~~chr21:36588530-36590785,
chr21:36503483-36505671~~chr21:36588474-36590657,
chr21:36503500-36505460~~chr21:36588511-36590472,
chr21:36503512-36505449~~chr21:36588675-36590309,
chr21:36503551-36505606~~chr21:36588646-36590268,
chr21:36503560-36505442~~chr21:36588600-36590428,
chr21:36503560-36505447~~chr21:36587180-36588484,
chr21:36503560-36505447~~chr21:36588574-36590548,
chr21:36503662-36505206~~chr21:36588817-36590277,
chr21:36503767-36505384~~chr21:36588667-36590330,
chr21:36503767-36505530~~chr21:36588716-36590491,
chr21:36503774-36505468~~chr21:36588596-36590469,
chr21:36503775-36505593~~chr21:36588685-36590306,
chr21:36575000-36600000~~chr21:36675000-36700000,
chr21:36575000-36600000~~chr21:36725000-36750000,
chr21:36575000-36600000~~chr21:36850000-36875000,
chr21:36575000-36600000~~chr21:36900000-36925000,
chr21:36575000-36600000~~chr21:37650000-37675000,
chr21:36584492-36585859~~chr21:36926709-36929084,
chr21:36584531-36585826~~chr21:36916655-36918813,
chr21:36584590-36585752~~chr21:36917143-36918319,