- Basic information
- CohesinDB ID: CDBP00418537
- Locus: chr21-36628239-36628880
-
Data sourse: GSE206145-NatGen2015, GSE67783, GSE86191
-
Cell type: Fibroblast, HCT-116, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.967
- Subunit: SA1,Rad21
-
CTCF binding site: CTCF
CTCF motif: False
- Genomic location: TES
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
-
Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
92% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
-
Chromatin annotation:
"14_ReprPCWk": 45%,
"15_Quies": 29%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
-
Co-bound Transcriptional factors: RUNX1, FOSL1, POU2F2, FOXA2, ZFX, XBP1, SMAD3, ZBTB48, WT1, ZSCAN5A, FOXA1, STAT1, SUZ12, HOXC5, YY1, RELA, KDM1A, ASCL1, JUNB, ATF3, MYC, RUNX2, AHR, SP140, PBX4, HIF1A, GRHL3, DAXX, ARNT, SMC3, STAT3, MAX, XRCC5, CBFA2T3, ZNF143, FOS, MITF, MED1, PLAG1, NR3C1, KLF4, CEBPB, TEAD1, KLF6, SCRT2, KDM5B, TP53, PITX3, USF2, MYOD1, NFKB1, BRD2, ZHX2, ELF3, JUN, CTCF, TCF12, BHLHE40, AR, IRF1, USF1, SOX4, HDAC2, RBAK, FLI1, BRD4, SCRT1, E2F1, MAZ, TEAD4, STAG1, ZNF316, FOSL2
- Target gene symbol (double-evidenced CRMs): SIM2,HLCS,CBR3,CHAF1B
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 3
- Related genes and loops
- Related gene:
ENSG00000159231,
ENSG00000159259,
ENSG00000159263,
ENSG00000159267,
- Related loop:
chr21:27500000-27525000~~chr21:36625000-36650000,
chr21:36125000-36150000~~chr21:36625000-36650000,
chr21:36400000-36425000~~chr21:36600000-36625000,
chr21:36400000-36425000~~chr21:36625000-36650000,
chr21:36419354-36421097~~chr21:36630022-36631930,
chr21:36500000-36525000~~chr21:36600000-36625000,
chr21:36500000-36525000~~chr21:36625000-36650000,
chr21:36503288-36505684~~chr21:36629965-36632036,
chr21:36600000-36625000~~chr21:36850000-36875000,
chr21:36625000-36650000~~chr21:36725000-36750000,
chr21:36625000-36650000~~chr21:36850000-36875000,
chr21:36625000-36650000~~chr21:36900000-36925000,
chr21:36625000-36650000~~chr21:36925000-36950000,
chr21:36625000-36650000~~chr21:38325000-38350000,
chr21:36629965-36632036~~chr21:36926513-36928814,
chr21:36629967-36632038~~chr21:36926717-36929094,
chr21:36629967-36632038~~chr21:37009098-37011099,
chr21:36629983-36632073~~chr21:36926687-36928814,
chr21:36629992-36632063~~chr21:36926698-36929094,
chr21:36629993-36632017~~chr21:36926436-36929179,
chr21:36629999-36631989~~chr21:36853631-36855655,
chr21:36629999-36631989~~chr21:36916779-36918440,
chr21:36629999-36631989~~chr21:36926695-36929067,
chr21:36629999-36631990~~chr21:36853672-36855599,
chr21:36629999-36631990~~chr21:36916781-36919095,
chr21:36630009-36632057~~chr21:36926465-36928856,
chr21:36630020-36631673~~chr21:36853741-36855359,
chr21:36630020-36631673~~chr21:36926943-36928561,
chr21:36630020-36631856~~chr21:36917076-36918400,
chr21:36630020-36631856~~chr21:36926866-36928715,
chr21:36630022-36631930~~chr21:36853698-36855512,
chr21:36630022-36631930~~chr21:36916749-36918779,
chr21:36630022-36631930~~chr21:36926649-36929131,
chr21:36630025-36631987~~chr21:36926664-36928827,
chr21:36630041-36631980~~chr21:36853648-36855688,
chr21:36630041-36631980~~chr21:36916655-36918813,
chr21:36630041-36631980~~chr21:36926706-36929092,
chr21:36630043-36632051~~chr21:36926683-36929117,
chr21:36630047-36631984~~chr21:36926713-36929121,
chr21:36630061-36631975~~chr21:36853777-36855522,
chr21:36630061-36631975~~chr21:36926705-36929148,
chr21:36630069-36631999~~chr21:36926719-36928757,
chr21:36630069-36632004~~chr21:36926505-36928808,
chr21:36630071-36632034~~chr21:36926986-36928735,
chr21:36630079-36631909~~chr21:36853738-36855617,
chr21:36630079-36631909~~chr21:36916843-36918429,
chr21:36630079-36631909~~chr21:36926924-36928703,
chr21:36630079-36631909~~chr21:37009057-37010910,
chr21:36630079-36631971~~chr21:36916825-36918710,
chr21:36630079-36631971~~chr21:36926751-36928873,
chr21:36630079-36632006~~chr21:36853685-36855567,
chr21:36630095-36631910~~chr21:36926753-36928677,
chr21:36630100-36631985~~chr21:36926700-36928696,
chr21:36630118-36632028~~chr21:36926726-36928770,
chr21:36630131-36631967~~chr21:36926642-36928684,
chr21:36630131-36631967~~chr21:36938670-36940602,
chr21:36630135-36631927~~chr21:36853724-36855502,
chr21:36630135-36631927~~chr21:36926709-36929084,
chr21:36630140-36632034~~chr21:36926410-36929350,
chr21:36630148-36631615~~chr21:36926948-36928575,
chr21:36630184-36631672~~chr21:36853762-36855538,
chr21:36630184-36631672~~chr21:36917051-36918370,
chr21:36630184-36631672~~chr21:36926932-36928694,
chr21:36630205-36631735~~chr21:36926885-36928641,
chr21:36630208-36631705~~chr21:36926942-36928578,
chr21:36630216-36631633~~chr21:36927027-36928493,
chr21:36630241-36631581~~chr21:36927031-36928663,