- Basic information
- CohesinDB ID: CDBP00418542
- Locus: chr21-36645284-36645814
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Data sourse: GSE67783, GSE86191, GSE98367
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Cell type: HCT-116, HSPC, Macrophage
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.967
- Subunit: SA1,Rad21,SMC1
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
92% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"14_ReprPCWk": 53%,
"15_Quies": 41%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: PLAG1, BRD4, USF2, DPF1, MAZ, USF1
- Target gene symbol (double-evidenced CRMs): HLCS,CHAF1B,SIM2,CBR3
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 10
- Related genes and loops
- Related gene:
ENSG00000159231,
ENSG00000159259,
ENSG00000159263,
ENSG00000159267,
- Related loop:
chr21:27500000-27525000~~chr21:36625000-36650000,
chr21:36125000-36150000~~chr21:36625000-36650000,
chr21:36400000-36425000~~chr21:36625000-36650000,
chr21:36500000-36525000~~chr21:36625000-36650000,
chr21:36625000-36650000~~chr21:36725000-36750000,
chr21:36625000-36650000~~chr21:36850000-36875000,
chr21:36625000-36650000~~chr21:36900000-36925000,
chr21:36625000-36650000~~chr21:36925000-36950000,
chr21:36625000-36650000~~chr21:38325000-38350000,
chr21:36639891-36641654~~chr21:36926687-36928814,
chr21:36640245-36641751~~chr21:36916843-36918429,
chr21:36650000-36675000~~chr21:36875000-36900000,
chr21:36650000-36675000~~chr21:36900000-36925000,
chr21:36650000-36675000~~chr21:36925000-36950000,