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Basic information

CohesinDB ID: CDBP00418546

Locus: chr21-36651157-36651225

Data sourse: GSE120943, GSE98367

Cell type: Monocytes, Macrophage

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.978

Subunit: SMC1

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: Intergenic

3D genome

TAD boundary: non-Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: False ChIA-PET loops: True

Compartment: 92% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "14_ReprPCWk": 58%, "15_Quies": 39%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: PGR, ZNF675, HMG20A, XBP1, FOXA1, HLF, SUZ12, PBX2, ZNF28, ZFHX2, TFAP4, ATF3, MITF, CDX2, JMJD1C, TEAD1, ZNF121, TRIM28, KLF6, SNAI2, NFE2L2, ELF1, ESR1, HNF1B, CTCF, JUN, EP300, MNT, GATA6, SOX4, TEAD4, KMT2B, TFAP2C, RBPJ, GLIS1, POU2F2, CHD8, ZSCAN5D, MYCN, POU5F1, TOP2A, ZNF263, ID3, ZBTB17, ZBTB48, ZSCAN5A, ZNF300, ERG, ONECUT1, MYC, SMARCA4, RAD21, GRHL3, NKX2-1, STAT3, XRCC5, SOX10, HNRNPH1, NR3C1, CEBPB, ESRRA, EZH2, GRHL2, SPI1, EHF, IRF1, HDAC2, GATA2, ZNF644, FLI1, ZNF766, NFIL3, ETV5, RUNX1, ZMYM2, CEBPA, ZFX, ZNF534, SMAD3, TET2, ERG3, PRDM10, CREBBP, ZNF384, CDK6, GATA4, ARNT, PBX4, NRF1, PRDM9, SMAD4, FOS, CDK8, TEAD3, MYB, SCRT2, NR1H2, SP1, ARID1A, POU2F3, HOXA9, SMC3, STAG1, PAX7, CBFA2T2, PPARG, FOXA2, WT1, ESR2, ZBTB33, HOXB13, ZKSCAN1, KDM1A, YY1, RELA, JUNB, SP140, HIF1A, GATA3, TAL1, MAX, SPIB, GATA1, CBX2, KLF4, CEBPG, KDM5B, TP53, PKNOX1, NFKB1, ELF3, BRD2, PAX3-FOXO1, AR, RXR, YAP1, ZNF366, HSF1, RNF2, BRD4, JUND, SCRT1, CUX1, MAZ

Target gene symbol (double-evidenced CRMs): HLCS

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 2

Related genes and loops

Related gene: ENSG00000159267,

eachgene

Deatailed information for cohesin site CDBP00418546