- Basic information
- CohesinDB ID: CDBP00418551
- Locus: chr21-36659026-36660000
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Data sourse: GSE67783, GSE86191, GSE98367, ENCSR000EGW, GSE206145, GSE120943, ENCSR153HNT
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Cell type: RPE, HCT-116, Monocytes, K-562, HSPC, Macrophage
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.933
- Subunit: SMC3,Rad21,SA1,SMC1
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
92% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"14_ReprPCWk": 58%,
"15_Quies": 21%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: ZNF426, POU2F2, PPARG, ZNF697, MYCN, CHD8, TOP2A, FOXA2, ZFX, XBP1, SMAD3, FOXA1, HOXB13, SMARCC1, PRDM10, ERG, RELA, SMARCA4, BRG1, GRHL3, HIF1A, PRDM9, GABPA, STAT3, XRCC5, ZSCAN4, SPIB, GATA1, MITF, ZNF750, CEBPB, EZH2, ESR1, BCL11A, SPI1, GATA6, ATF1, ARID1A, SIX2, BRD4, FOXP1, TEAD4, ZNF34, TFAP2C
- Target gene symbol (double-evidenced CRMs): HLCS
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 7
- Related genes and loops
- Related gene:
ENSG00000159267,
- Related loop:
chr21:36650000-36675000~~chr21:36875000-36900000,
chr21:36650000-36675000~~chr21:36900000-36925000,
chr21:36650000-36675000~~chr21:36925000-36950000,
chr21:36661089-36662805~~chr21:36926942-36928692,
chr21:36661117-36662769~~chr21:36927009-36928504,
chr21:36661133-36662988~~chr21:36853672-36855599,
chr21:36661144-36662963~~chr21:36916775-36918452,
chr21:36661144-36662963~~chr21:36926710-36929115,
chr21:36661151-36662948~~chr21:36926649-36929131,
chr21:36661153-36662982~~chr21:36916793-36918416,
chr21:36661153-36662982~~chr21:36926713-36929121,
chr21:36661155-36662934~~chr21:36926465-36928856,
chr21:36661160-36663028~~chr21:36926687-36928814,
chr21:36661164-36662953~~chr21:36926726-36928770,
chr21:36661178-36662981~~chr21:36916765-36918736,
chr21:36661178-36662981~~chr21:36926664-36928827,
chr21:36661187-36662898~~chr21:36926505-36928808,
chr21:36661192-36662935~~chr21:36926698-36929094,
chr21:36661198-36662971~~chr21:36926727-36928820,
chr21:36661203-36662789~~chr21:36853762-36855538,
chr21:36661239-36662859~~chr21:36853733-36855333,
chr21:36661375-36662830~~chr21:36917122-36918453,