- Basic information
- CohesinDB ID: CDBP00418552
- Locus: chr21-36660688-36662628
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Data sourse: ENCSR230ZWH, ENCSR000FAD, ENCSR000BSB, ENCSR000EGW, GSE131606, ENCSR330ELC, ENCSR000BUC, ENCSR000DYE, ENCSR917QNE, GSE115602, GSE86191, GSE101921, ENCSR806UKK, GSE112028, GSE130135, ENCSR199XBQ, GSE94872, ENCSR895JMI, GSE118494, ENCSR000EEG, ENCSR338DUC, ENCSR247LSH, GSE105004, ENCSR676MJK, ENCSR054FKH, GSE83726, ENCSR748MVX, ENCSR000ECS, ENCSR000BLD, GSE104888, GSE126634, GSE132649, GSE103477, GSE108869, GSE143937, GSE138405, GSE135093, GSE106870, ENCSR193NSH, GSE206145, ENCSR000ECE, ENCSR620NWG, ENCSR767DFK, ENCSR984DZW, GSE55407, ENCSR000BTQ, GSE129526, ENCSR537EFT, ENCSR760NPX, ENCSR000BLY, ENCSR150EFU, GSE121355, GSE111537, GSE25021, GSE122299, GSE115250, GSE76893, GSE145327, GSE76815, ENCSR000BMY, ENCSR000EHX, ENCSR635OSG, GSE97394, ENCSR217ELF, GSE131956, GSE110061, ENCSR000HPG, GSE111913, ENCSR335RKQ, ENCSR000EDE, GSE50893, ENCSR481YWD, GSE206145-GSE177045, GSE72082, ENCSR501LQA, GSE105028, ENCSR000EDW, ENCSR000EFJ, ENCSR000BTU, ENCSR000BKV, GSE152721, GSE206145-NatGen2015, GSE138105, ENCSR703TNG, GSE116344, ENCSR768DOX, ENCSR879KXD, ENCSR000BLS, ENCSR000EHW, GSE155828, ENCSR981FDC, ENCSR807WAC, ENCSR495WGO, ENCSR167MTG, ENCSR853VWZ, ENCSR956LGB, ENCSR944ZCT, ENCSR153HNT, GSE68388, GSE126990
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Cell type: MDM, RH4, GM10847, GM2610, SLK, CVB-hiPSC, GM19240, CVI-hiPSC, Liver, Transformed-RPE1, HuCC-T1, H9-hESC, RPE, GM2630, HMEC, Fibroblast, THP-1, Ishikawa, GM12890, HeLa-S3, GM2255, IMR-90, K-562, GM18486, DKO, GM18526, H1-hESC, SNYDER, GM18505, GM12878, GM12891, GM2588, GBM39, SK-N-SH, GM19239, HeLa-Tet-On, GM19193, RT-112, HAP1, GM19099, HUES64, MCF-7, GM12892, T-47D, Hela-Kyoto, HCT-116, MCF-10A, HEK293T, Hep-G2, A-549, HUVEC, HCAEC, GM19238, HeLa, TC-71, OCI-AML-3, GM18951
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 66% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.356
- Subunit: NIPBL,SA1,Rad21,SMC1,SMC3ac,SA2,Mau2,SMC3
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
92% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"14_ReprPCWk": 59%,
"15_Quies": 15%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: RELA, ASCL1, POU5F1, BRG1, SCRT2, ZFX, GRHL3, ARNT, WT1, MAZ, SMC3, EED
- Target gene symbol (double-evidenced CRMs): HLCS
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 13
- Related genes and loops
- Related gene:
ENSG00000159267,
- Related loop:
chr21:36650000-36675000~~chr21:36875000-36900000,
chr21:36650000-36675000~~chr21:36900000-36925000,
chr21:36650000-36675000~~chr21:36925000-36950000,
chr21:36661089-36662805~~chr21:36926942-36928692,
chr21:36661117-36662769~~chr21:36927009-36928504,
chr21:36661133-36662988~~chr21:36853672-36855599,
chr21:36661144-36662963~~chr21:36916775-36918452,
chr21:36661144-36662963~~chr21:36926710-36929115,
chr21:36661151-36662948~~chr21:36926649-36929131,
chr21:36661153-36662982~~chr21:36916793-36918416,
chr21:36661153-36662982~~chr21:36926713-36929121,
chr21:36661155-36662934~~chr21:36926465-36928856,
chr21:36661160-36663028~~chr21:36926687-36928814,
chr21:36661164-36662953~~chr21:36926726-36928770,
chr21:36661178-36662981~~chr21:36916765-36918736,
chr21:36661178-36662981~~chr21:36926664-36928827,
chr21:36661187-36662898~~chr21:36926505-36928808,
chr21:36661192-36662935~~chr21:36926698-36929094,
chr21:36661198-36662971~~chr21:36926727-36928820,
chr21:36661203-36662789~~chr21:36853762-36855538,
chr21:36661239-36662859~~chr21:36853733-36855333,
chr21:36661375-36662830~~chr21:36917122-36918453,