- Basic information
- CohesinDB ID: CDBP00418553
- Locus: chr21-36662944-36663906
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Data sourse: ENCSR000BTU, GSE206145, GSE206145-NatGen2015, GSE68388, GSE116344, GSE165895
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Cell type: RPE, Fibroblast, RH4, Ishikawa, HuCC-T1, HFFc6
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 2% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.933
- Subunit: SA1,Rad21,SMC1
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
92% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"14_ReprPCWk": 34%,
"13_ReprPC": 31%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: SOX2, XBP1, FOXA1, SUZ12, ZNF28, ZNF596, ATF3, CHD7, ATF4, ZSCAN4, ZNF467, ELF1, TRIM28, TEAD1, RBM39, OCA2, JUN, CTCF, E2F4, ZNF92, GLIS1, JARID2, MYCN, TOP2A, ZBTB17, DUX4, ZBTB48, DDX5, ERG, MYC, SMARCA4, NKX2-1, GABPA, STAT3, XRCC5, IKZF1, ARNTL, CEBPB, ESRRA, EZH2, EBF3, ZNF436, SPI1, FLI1, MXI1, HCFC1R1, MRTFB, MYF5, CEBPA, EZH2phosphoT487, ZFX, SMAD3, ZNF770, CBX8, ZNF33B, SMARCC1, TWIST1, ZNF384, RUNX2, OSR2, PBX4, ARNT, FOS, TEAD3, SCRT2, ZNF3, KLF9, L3MBTL2, PCGF2, BCOR, TCF3, FOXP1, SS18, ZSCAN16, WT1, HOXB13, YY1, RELA, JUNB, BRG1, SP140, ZIC2, HIF1A, ZFP36, OTX2, MAX, ZNF143, HAND2, CBX2, CEBPG, KDM5B, ZNF334, MYOD1, AR, RXR, HSF1, RNF2, ZBTB26, JUND, BRD4, MAZ, ZNF24, AHR
- Target gene symbol (double-evidenced CRMs): HLCS
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 4
- Related genes and loops
- Related gene:
ENSG00000159267,
- Related loop:
chr21:36650000-36675000~~chr21:36875000-36900000,
chr21:36650000-36675000~~chr21:36900000-36925000,
chr21:36650000-36675000~~chr21:36925000-36950000,
chr21:36661089-36662805~~chr21:36926942-36928692,
chr21:36661117-36662769~~chr21:36927009-36928504,
chr21:36661133-36662988~~chr21:36853672-36855599,
chr21:36661144-36662963~~chr21:36916775-36918452,
chr21:36661144-36662963~~chr21:36926710-36929115,
chr21:36661151-36662948~~chr21:36926649-36929131,
chr21:36661153-36662982~~chr21:36916793-36918416,
chr21:36661153-36662982~~chr21:36926713-36929121,
chr21:36661155-36662934~~chr21:36926465-36928856,
chr21:36661160-36663028~~chr21:36926687-36928814,
chr21:36661164-36662953~~chr21:36926726-36928770,
chr21:36661178-36662981~~chr21:36916765-36918736,
chr21:36661178-36662981~~chr21:36926664-36928827,
chr21:36661187-36662898~~chr21:36926505-36928808,
chr21:36661192-36662935~~chr21:36926698-36929094,
chr21:36661198-36662971~~chr21:36926727-36928820,
chr21:36661203-36662789~~chr21:36853762-36855538,
chr21:36661239-36662859~~chr21:36853733-36855333,
chr21:36661375-36662830~~chr21:36917122-36918453,