- Basic information
- CohesinDB ID: CDBP00418556
- Locus: chr21-36667005-36667797
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Data sourse: GSE67783, ENCSR153HNT
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Cell type: K-562, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 0% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.978
- Subunit: SA1
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
92% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"14_ReprPCWk": 55%,
"13_ReprPC": 27%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: RUNX1, GLIS1, TRP47, CBFA2T2, SMC1A, ZSCAN5D, ZNF263, MYCN, FOXA2, RUNX1T1, ZFX, POU5F1, XBP1, SIRT6, ZBTB48, WT1, STAT1, HINFP, ZSCAN5A, FOXA1, ERG3, TET2, ERG2, SP4, HOXB13, SMARCC1, ZFHX2, ERG, YY1, OGG1, AHR, ATF3, BRG1, MCM3, SP140, ZFP36, HIF1A, GRHL3, SOX11, ZIC2, CBFB, SMC3, SMAD4, STAT3, TOP2A, TP63, NCAPH2, PRDM14, ZNF143, ZNF600, ZNF736, CBX2, CEBPB, NR2F1, EZH2, LMO2, ESR1, PKNOX1, ZNF79, EGR2, CTCF, SPI1, GATA6, RXR, DEK, HSF1, FLI1, BRD4, MAZ, AATF, HCFC1R1, TEAD4, PRDM6, NFKBIA, STAG1, TFAP2C, EED
- Target gene symbol (double-evidenced CRMs): HLCS
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 5
- Related genes and loops
- Related gene:
ENSG00000159267,
- Related loop:
chr21:36650000-36675000~~chr21:36875000-36900000,
chr21:36650000-36675000~~chr21:36900000-36925000,
chr21:36650000-36675000~~chr21:36925000-36950000,
chr21:36661089-36662805~~chr21:36926942-36928692,
chr21:36661117-36662769~~chr21:36927009-36928504,
chr21:36661133-36662988~~chr21:36853672-36855599,
chr21:36661144-36662963~~chr21:36916775-36918452,
chr21:36661144-36662963~~chr21:36926710-36929115,
chr21:36661151-36662948~~chr21:36926649-36929131,
chr21:36661153-36662982~~chr21:36916793-36918416,
chr21:36661153-36662982~~chr21:36926713-36929121,
chr21:36661155-36662934~~chr21:36926465-36928856,
chr21:36661160-36663028~~chr21:36926687-36928814,
chr21:36661164-36662953~~chr21:36926726-36928770,
chr21:36661178-36662981~~chr21:36916765-36918736,
chr21:36661178-36662981~~chr21:36926664-36928827,
chr21:36661187-36662898~~chr21:36926505-36928808,
chr21:36661192-36662935~~chr21:36926698-36929094,
chr21:36661198-36662971~~chr21:36926727-36928820,
chr21:36661203-36662789~~chr21:36853762-36855538,
chr21:36661239-36662859~~chr21:36853733-36855333,
chr21:36661375-36662830~~chr21:36917122-36918453,