- Basic information
- CohesinDB ID: CDBP00418557
- Locus: chr21-36668625-36669819
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Data sourse: ENCSR000BLD, GSE67783, GSE86191, GSE105028, GSE206145, ENCSR153HNT
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Cell type: RPE, H1-hESC, HCT-116, K-562, HSPC, H9-hESC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 2% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.933
- Subunit: SA1,Rad21
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
92% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"14_ReprPCWk": 50%,
"13_ReprPC": 30%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: RUNX1, GLIS1, TRP47, CBFA2T2, SMC1A, ZSCAN5D, ZNF263, MYCN, FOXA2, RUNX1T1, ZFX, POU5F1, XBP1, SIRT6, ZBTB48, WT1, STAT1, HINFP, ZSCAN5A, FOXA1, ERG3, TET2, ERG2, SP4, HOXB13, SMARCC1, ZFHX2, ERG, YY1, OGG1, AHR, ATF3, BRG1, MCM3, SP140, ZFP36, HIF1A, GRHL3, SOX11, ZIC2, CBFB, SMC3, SMAD4, STAT3, TOP2A, TP63, NCAPH2, PRDM14, ZNF143, ZNF600, ZNF736, CBX2, CEBPB, NR2F1, EZH2, LMO2, ESR1, PKNOX1, ZNF79, EGR2, CTCF, SPI1, GATA6, RXR, DEK, HSF1, FLI1, BRD4, MAZ, AATF, HCFC1R1, TEAD4, PRDM6, NFKBIA, STAG1, TFAP2C, EED
- Target gene symbol (double-evidenced CRMs): HLCS
- Function elements
- Human SNPs: Testicular_cancer
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 8
- Related genes and loops