- Basic information
- CohesinDB ID: CDBP00418562
- Locus: chr21-36685090-36686439
-
Data sourse: GSE67783, ENCSR000BKV, GSE36578, ENCSR000EGW, GSE206145
-
Cell type: K-562, RPE, HSPC, BGO3
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 2% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.956
- Subunit: SA1,Rad21,SMC1,Mau2,SMC3
-
CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
-
Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
92% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
-
Chromatin annotation:
"14_ReprPCWk": 51%,
"13_ReprPC": 35%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
-
Co-bound Transcriptional factors: PGR, CHD8, MYCN, ZFX, XBP1, ZNF317, ZBTB48, SUZ12, DDX5, ERG, RELA, ZNF384, ZNF362, ARNT, HIF1A, ZNF429, GRHL3, MAFB, SP2, GATA1, MED1, ELF1, HNRNPL, ETV1, PIAS1, NEUROG2, EZH2, MYOD1, ZNF22, BAF155, SMC3, TFAP2C
- Target gene symbol (double-evidenced CRMs): RUNX1,CHAF1B,HLCS,CBR3
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 9
- Related genes and loops
- Related gene:
ENSG00000159216,
ENSG00000159231,
ENSG00000159259,
ENSG00000159267,
- Related loop:
chr21:33025000-33050000~~chr21:36675000-36700000,
chr21:34875000-34900000~~chr21:36675000-36700000,
chr21:36125000-36150000~~chr21:36675000-36700000,
chr21:36400000-36425000~~chr21:36675000-36700000,
chr21:36500000-36525000~~chr21:36675000-36700000,
chr21:36575000-36600000~~chr21:36675000-36700000,
chr21:36675000-36700000~~chr21:36900000-36925000,
chr21:36675000-36700000~~chr21:36925000-36950000,